Involvement of follicular stem cells in forming not only the follicle but also the epidermis.

By Gina A. Taylor, M. Lehrer, P. Jensen, T. Sun, R. Lavker. Cell, 2000

1,097 citations recorded by the source corpus.

Subfields: Cell Biology, Radiology, Nuclear Medicine and Imaging, Urology

View Paper: https://www.semanticscholar.org/paper/a14120a23a1896fff5dc1020086e11978ded371e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Elaine Fuchs
2. C. Blanpain
3. H. Pasolli
4. V. Horsley
5. S. Morrison
6. Hans Clevers
7. Linheng Li
8. T. Xie

In Radiology, Nuclear Medicine and Imaging

1. Elaine Fuchs
2. C. Blanpain
3. Hans Clevers

In Urology

1. Hans Clevers
2. Elaine Fuchs
3. C. Blanpain
4. H. Pasolli
5. V. Horsley
6. Linheng Li
7. Y. Hsu
8. S. Morrison

Citations in the corpus

• Stem cell niche: structure and function. (2005, background): “…rise to daughter cells that either migrate upward to serve as epidermal progenitors for generating epidermal cells during wound repair or migrate downward to convert to hair-matrix progenitors, which further give rise to the hair shaft (Niemann & Watt 2002, Oshima et al. 2001, Taylor et al. 2000).”
• Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. (2004, background): “Pulse-chase experiments with lainhibited in the niche but can self-renew in vitro and beled nucleotides (Cotsarelis et al., 1990; Morris and make epidermis and hair when grafted. These findings Potten, 1999; Taylor et al., 2000) or transgenic expressuggest that the niche microenvironment imposes in-”
• Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. (2001, positive): “This follicular location in the neck region is a common location for the “bulge,” which has recentlybeen demonstratedto bea sitefor skinprogeni-tor cells (Taylor et al., 2000).”
• Identification of the haematopoietic stem cell niche and control of the niche size (2003, background): “As LT-HSCs are quiescent or slow cycling, they are able to retain labelled nucleotides for a relatively long period and can be identified as BrdU-LTR (long-term retaining) cell”
• Epithelial stem cells: turning over new leaves. (2007, positive): “…during the normal cyclic periods of hair growth but also in conditions of hyperproliferation of sebaceous glands (Horsley et al., 2006) and in the repair of the interfollicular epidermis following wounding (Ito et al., 2005; Levy et al., 2005; Taylor et al., 2000; Tumbar et al., 2004) (Figure 2).”
• Stem cells find their niche (2001, background): “Cell marking and follicle transplantation experiments have shown that the bulge contains stem cells that repopulate the matrix region, form new sebaceous glands, and replace epidermal stem cell”
• A Two-Step Mechanism for Stem Cell Activation during Hair Regeneration (2009, positive): “In the adult skin, slowcycling, relatively undifferentiated SCs exist within a niche known as the bulge, located below the sebaceous gland in the outer root sheath (ORS) of the hair follicle (HF) (Cotsarelis et al., 1990; Oshima et al., 2001; Taylor et al., 2000).”
• Epidermal stem cells of the skin. (2006, background): “To evaluate whether bulge LRCs have this capacity, Taylor et al. (2000) extended their double-labeling techniques to wound-healing experiments.”