Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche.

By C. Blanpain, W. Lowry, A. Geoghegan, Lisa Polak, Elaine Fuchs. Cell, 2004

1,462 citations recorded by the source corpus.

Subfields: Molecular Biology, Rehabilitation, Urology

View Paper: https://www.semanticscholar.org/paper/ea686bdd623ad6d4dca7b49b09466b217b9d1360

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Hans Clevers
2. Elaine Fuchs
3. C. Blanpain
4. S. Morrison
5. V. Horsley
6. Hugo J. G. Snippert
7. Nick Barker
8. H. Pasolli

In Rehabilitation

1. Elaine Fuchs
2. H. Pasolli
3. Hans Clevers
4. Y. Hsu
5. V. Horsley
6. C. Blanpain
7. N. Stokes

In Urology

1. Elaine Fuchs
2. Hans Clevers
3. H. Pasolli
4. C. Blanpain
5. V. Horsley
6. S. Morrison
7. Y. Hsu
8. A. Spradling

Citations in the corpus

• Tumour stem cells and drug resistance (2005, background): “They also require specific environments comprising other cells, stroma and growth factors for their surviva”
• Epithelial stem cells: turning over new leaves. (2007, positive): “In the intestine and mammary gland, Tcf4 is prominently expressed in the stem compartment (Barker et al., 1999); in the follicular stem cell niche, Tcf4 is expressed in conjunction with Tcf3 (Blanpain et al., 2004;Nguyen et al., 2006).”
• Identification of bronchioalveolar stem cells in normal lung and lung cancer. (2005, neutral): “Furthermore, some studies that include in vivo data have relied on expansion of putative stem cells in culture prior to engraftment, raising the possibility that culturing changed the potency of the isolated cell population (Blanpain et al., 2004; Gage et al., 1995; Spangrude et al., 1995).”
• Characterization and isolation of stem cell-enriched human hair follicle bulge cells. (2005, background): “Finally, isolated bulge cells demonstrated high colony-forming efficiency (10, 11, 15).”
• Leukaemia stem cells and the evolution of cancer-stem-cell research (2005, background): “The recent discovery of many more tissue-specific stem cell”
• Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. (2008, background): “Epithelial stem cells within the bulge of the hair follicle have been enriched based on expression of the glycoprotein CD34 and retention of a histone-green fluorescent protein (GFP) label (Blanpain et al., 2004) (Figure 3).”
• Tracking adult stem cells (2011, background): “There are other examples of well-described adult stem cells—such as muscle satellite cells—that asymmetrically segregate their DNA strands”
• Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells (2009, methodology): “Cell Culture Enzymatic separation of epidermis from skins and primary P0 MK culturing were as described (Blanpain et al., 2004).”