Roles of heat-shock proteins in innate and adaptive immunity

By Pramod Kumar Srivastava. Nature reviews. Immunology, 2002

1,125 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Parasitology

View Paper: https://www.semanticscholar.org/paper/a0fd1ab2ccc5f476115fa74900579ff9c4d97304

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Citations in the corpus

Necrosis: a specific form of programmed cell death? (2003, background): “[163] P.”
The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. (2006, background): “Factors that induce innate immune responses similar to microbial pathogens include heat shock proteins (Asea et al., 2002; Ohashi et al., 2000; Srivastava, 2002), hyaluronic acid (Termeer et al.”
Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets (2018, background): “Analysis of the weights in the mRNA revealed that this factor tagged a set of genes enriched for oxidative stress and senescence pathways (Figs 2F and EV2A), with the top weights corresponding to heat-shock proteins (HSPs; Fig EV2B and C), genes that are essential for protein folding and are up-regu”
Cross‐presentation, dendritic cell subsets, and the generation of immunity to cellular antigens (2004, background): “As a third mechanism for antigen access to the crosspresentation pathway, it is worth mentioning that several studies have illustrated the capacity of HSPs to efficiently prime CTL immunity (44).”
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. (2006, neutral): “[196,203–205].”
The endogenous Toll–like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer (2009, background): “This review focuses on the recent advances in understanding the function of S100A8 and S100A9 as endogenous DAMPs.”
Immunotherapy: past, present and future (2003, background): “In yet another approach, the antigen is complexed to members of the heat-shock protein family that enter the dendritic cell through CD91 (α2-macroglobulin receptor), an approach that substantially enhances the immunogenicity of the antigen by activating APCs and targeting them to the MHC processing ”