Elements of a neurobiological theory of the hippocampus: the role of activity-dependent synaptic plasticity in memory.

By Richard G. M. Morris, Edvard I. Moser, G. Riedel, Stephen J. Martin, J. Sandin, Mark Day, C. O’Carroll. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2003

498 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/a09ee1abd35f0a70e7719bcd9072ad38a4e3c7a3

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Citations in the corpus

Integrating Memories in the Human Brain: Hippocampal–Midbrain Encoding of Overlapping Events (2008, background): “Midbrain dopamine neurons project not only to the striatum but also to the hippocampus (Gasbarri et al., 1994; Swanson, 1982), where dopamine has been shown to modulate plasticity (Frey et al., 1990; Morris et al., 2003; Otmakhova and Lisman, 1996).”
The mechanisms for pattern completion and pattern separation in the hippocampus (2013, background): “…the hippocampus show associative modification as shown by long-term potentiation, and this synaptic modification appears to be involved in learning (see Morris, 1989, 2003; Morris et al., 2003; Nakazawa et al., 2003, 2004; Lynch, 2004; Andersen et al., 2007; Wang and Morris, 2010; Jackson, 2013).”
Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus. (2007, unknown): “…of the protein synthesis-dependent late phase of long-term potentiation (L-LTP) (Kang et al., 1997; Korte et al., 1995; Pang et al., 2004; Patterson et al., 1996; Poo, 2001; Tyler et al., 2002), a form of synaptic plasticity thought to underlie LTM (Morris et al., 2003; Whitlock et al., 2006).”
EPIGENETIC REGULATION OF BDNF GENE TRANSCRIPTION IN THE CONSOLIDATION OF FEAR MEMORY (2008, background): “It is well appreciated that NMDA receptor activation is important for the acquisition and consolidation of memories (Morris et al., 2003).”
Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory. (2009, methodology): “A gradual decay with a similar time course is also observed in hippocampal long-term potentiation (LTP) (Castro et al., 1989; Villarreal et al., 2002), a putative cellular model of learning and memory (Kandel, 2001; Morris et al., 2003; Okada et al., 2009).”
Reactivation of neural ensembles during the retrieval of recent and remote memory. (2013, unknown): “Retrieving these memories is assumed to involve reactivation of hippocampal and neocortical networks that were established during learning [1–3].”
Pattern separation, completion, and categorisation in the hippocampus and neocortex. (2016, background): “…as shown by long-term potentiation, and this synaptic modification appears to be involved in learning (see Andersen et al., 2007; Jackson, 2013; Lynch, 2004; Morris, 1989, 2003; Morris et al., 2003; Nakazawa, McHugh, Wilson, & Tonegawa, 2004; Nakazawa et al., 2003; Wang & Morris, 2010).”
The organization of recent and remote memories (2005, background): “Initially, the hippocampus is thought to integrate information from distributed, but relatively independent, cortical modules that represent the various features of an experience, and then to rapidly fuse these various features into a coherent memory trac”
The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law (2007, background): “…support for this idea is the ﬁnding that, unlike stress, hippocampal lesion or inactivation produces a general impairment of spatial learning and memory in rats (O’Keefe and Nadel [278]; Olton et al. [279]; Steele and Morris [280]; Diamond et al. [52]; Morris et al. [281]; Nakazawa et al. [282]).”
ReviewThe Hippocampal-VTA Loop : Controlling the Entry of Information into Long-Term Memory (2005, unknown): “Activation of this kinase, in turn, acts to inhibit phosphatase activity and thereby enhances the (Figure 3A) is noteworthy because of the use of a second input pathway that was not tetanized; the stability phosphorylation of CaMKII (Blitzer et al., 1998), a molecule that is necessary and sufficient”
Elements of a neurobiological theory of hippocampal function: the role of synaptic plasticity, synaptic tagging and schemas (2006, background): “It is vital that traces representing information about such episodes are encoded and stored in real time, as they happen, a process I and my research colleagues have characterized as the ‘automatic recording of attended experience’ (Morris & Frey, 1997; Morris, 2001; Morris et al., 2003).”
Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS). (2014, unknown): “This may induce an activity-dependent modulation according to phase-locking synchrony between cortical oscillations and the pattern of the stimulation (Bear and Kirkwood, 1993; Morris et al., 2003).”
TrkB signalling pathways in LTP and learning (2009, background): “This has made L-LTP induction an attractive candidate for the molecular analogue of long-term memory (LTM”
Reward-related fMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation (2005, background): “Encoding of novel stimuli is associated with synaptic plasticity processes in the hippocampus for which the induction of long-term potentiation (LTP) is generally believed to play an important role (Morris and Frey, 1997; Frey and Morris, 1998; Morris et al., 2003; Pittenger and Kandel, 2003; Straub”