The core gut microbiome, energy balance and obesity

By Peter J. Turnbaugh, Jeffrey I. Gordon. Journal of Physiology, 2009

1,000 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/9aaefaf095d334fdc9bd7c019ee00a68f2808717

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Citations in the corpus

Association between body mass index and Firmicutes/Bacteroidetes ratio in an adult Ukrainian population (2017, background): “individuals have distinct microbiota composition, with measurable difference in the ability to extract energy from the food and to store those energy as the fat [12].”
Beyond the Venn diagram: the hunt for a core microbiome. (2012, background): “Collectively, these studies provide preliminary evidence of cores, and the resulting enthusiasm has produced almost as many reviews, commentary and opinion articles as primary research (e.g. Tschop et al., 2009; Turnbaugh and Gordon, 2009; Vael and Desager, 2009; Bäckhed, 2010; Benson et al., 2010; ”
U.S. immigration westernizes the human gut microbiome (2018, result): “As in other studies (Sze and Schloss, 2016; Turnbaugh and Gordon, 2009), we found that lower phylogenetic diversity was associated with obesity across all major study groups (unbalanced two-way ANOVA, p = 0.”
Characterization of the Gut Microbiome Using 16S or Shotgun Metagenomics (2016, background): “…diversity and/or imbalances in the gut microbiome have been associated with a variety of phenotypes, including obesity (Turnbaugh et al., 2009; Turnbaugh and Gordon, 2009), inflammatory bowel diseases (IBD) (Knights et al., 2013; Huttenhower et al., 2014b; Kostic et al., 2014; Norman et al.,…”
Carbohydrate metabolism in Bifidobacteria (2011, background): “In addition, various studies have shown that the adult human microbiota is specific to each individual, and furthermore depends on age, diet, genetic background, physiological state, microbial interactions and environmental factors [22, 33, 102, 134, 148].”
Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models (2010, background): “Furthermore, switching from a low-fat to a high-fat diet resulted in a rapid and dramatic shift in the structure of the gut microbiota inmice in a single day.(23)These studies suggest that diet plays an important role in modulating the gut microbiota.”
Gut microbiome-host interactions in health and disease (2011, background): “2009 [39,100] 154 (31 MZ and 23 DZ female twin pairs and their mothers n = 46, twins concordant for obesity or leanness) 454 Pyrosequencing 9,920 near full-length and 1,937,461 partial bacterial 16S rRNA sequences Gut microbiome shared among family members; degree of co-variation between adult MZ an”
Kupffer Cells in the Liver (2013, positive): “Similar associations between changes in the gut micro-biome in mouse models of obesity and fatty liver have also been identiﬁed (26,142).”
Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. (2011, background): “interpersonal variation noted in other human studies (28, 29).”
Bacterial community assembly based on functional genes rather than species (2011, background): “other complex host-associated microbial communities, such as the human microbiome, where a consistent core of functional genes is detected across hosts (85), but species-level community composition is highly variable (86).”