Morpho-functional characterization of neuronal cells at different stages of maturation in granule cell layer of adult rat dentate gyrus.

By P. Ambrogini, D. Lattanzi, S. Ciuffoli, D. Agostini, L. Bertini, Vilberto Stocchi, S. Santi, R. Cuppini. 2004

224 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Developmental Neuroscience

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Citations in the corpus

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? (2010, background): “Around 4–6 weeks of age, together with the gradual maturation of their physiology and connectivit”
Integration of New Neurons into Functional Neural Networks (2006, background): “Young, newborn granule cells ( 3 weeks old) exhibit an enhanced excitability and increased Ca 2 conductance (Ambrogini et al., 2004; Schmidt-Hieber et al., 2004) and a lower threshold for LTP induction (Schmidt-Hieber et al., 2004) than their mature, already existing granule cell neighbors.”
Modification of hippocampal circuitry by adult neurogenesis (2012, background): “For example, at 6–8 weeks of age, newborn neurons display overall morphological and functional characteristics very similar to that of fully mature dentate granule cells (van Praag et al., 2002; Ambrogini et al., 2004; Schmidt-Hieber et al., 2004).”
GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations. (2007, background): “In another study (12), two GABA currents evoked in”
Spatial Learning Depends on Both the Addition and Removal of New Hippocampal Neurons (2007, background): “]. After the first week of maturation, they also receive depolarizing GABA inputs [”
Modeling new neuron function: a history of using computational neuroscience to study adult neurogenesis (2011, background): “Furthermore, at the start of the simulation, all the GCs in the network were initialized as naı¨ve, with the network eventually maturing to an adult-like state.”
Adult neurogenesis and the plasticity of the dentate gyrus network (2011, background): “This anatomical gradient is also consistent with electrophysiological studies showing that neurons with immature functional properties and with an increased degree of activitydependent synaptic plasticity are primarily located in the innermost layers of the GCL (Wang et al., 2000; Ambrogini et al., ”
Sparse activity of identified dentate granule cells during spatial exploration (2016, background): “…the complex cone-shape of the dendritic arbor and, in the few cases where axons were recovered (e.g. Figure 3A), the presence of long-range axons and mossy boutons (Ambrogini et al., 2004; Schmidt-Hieber et al., 2004; Espósito et al., 2005; Zhao et al., 2006; Pernı́a-Andrade and Jonas, 2014).”
Synaptic integration and plasticity of new neurons in the adult hippocampus (2008, background): “Electrophysiological analysis has shown the expression of ionotropic glutamate receptors in immature neurons (Ambrogini et al. 2004; Overstreet Wadiche et al. 2005; Tozuka et al. 2005).”
Neuronal Differentiation in the Adult Hippocampus Recapitulates Embryonic Development (2005, result): “Our results also present conclusive evidence supporting the recent observations that adult DGCs with high Rinput display only GABA-mediated afferents (Ambrogini et al., 2004), and that adult hippocampal NPCs expressing GFP under the nestin promoter exhibit GABAergic currents (Wang et al., 2005).”
Hippocampal granule cells opt for early retirement (2010, background): “…on experimental paradigm, can be observed to occur from 2 weeks to 5 months (Wang et al., 2000; Snyder et al., 2001; van Praag et al., 2002; Ambrogini et al., 2004; Schmidt-Hieber et al., 2004; Esposito et al., 2005; Ramirez-Amaya, 2005; Song et al., 2005; Ge et al., 2006;…”