An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans

By N. Lau, Lee P. Lim, E. Weinstein, David P. Bartel. Science, 2001

3,588 citations recorded by the source corpus.

Subfields: Aging, Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9942964162ef60f639946f70f4ad31da085ae75e

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Citations in the corpus

Perspective: machines for RNAi. (2005, background): “1; Lee et al. 1993; Pasquinelli et al. 2000; Reinhart et al. 2000, 2002; Aravin et al. 2001, 2003; Lagos-Quintana et al. 2001, 2002, 2003; Lau et al. 2001; Lee and Ambros 2001; Llave et al. 2002a; Mourelatos et al. 2002; Reinhart and Bartel 2002; Brennecke and Cohen 2003; Brennecke et al. 2003;…”
Non‐coding RNAs: regulators of disease (2010, background): “Although this phenomenon, termed RNA interference (RNAi), was originally thought to be restricted to exogenous dsRNAs, it soon became clear that plants and animals produce a dazzling array of endogenous small interfering RNAs (siRNAs), microRNAs (miRNAs) and PIWIinteracting RNAs (piRNAs) [14–17,32–3”
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. (2005, neutral): “(Lau et al., 2001).”
3’ end processing of a long nuclear-retained non-coding RNA yields a tRNA-like cytoplasmic RNA (2008, neutral): “To clone the 3’ ends of the mascRNA and MALAT1 transcripts, the Modban oligo (IDT DNA Technologies, Coralville, Iowa) was ligated to the 3’ ends of total RNA similar to a previously described procedure (Lau et al., 2001).”
The Genome Sequence of Caenorhabditis briggsae: A Platform for Comparative Genomics (2003, background): “An additional cluster contains six C. elegans paralogs to mir-35 and mir-41, versus eight in C. briggsae, as previously reported (Lau et al. 2001).”
Small RNAs and Their Roles in Plant Development (2009, background): “In 2001, tens of miRNAs were found in several animal species through direct cloning (Lagos-Quintana et al. 2001, Lau et al. 2001, Lee & Ambros 2001).”
MicroRNAs in human cancer. (2013, neutral): “[ 5, 7, 8, 31– 34 ] ).”
Computational identification of microRNA targets (2004, background): “…of miR- NAs for development has been further established by the notion that many miRNAs appear to have temporal or tissue-specific patterns of gene expression (Houbaviy et al., 2003; Lau et al., 2001; Lagos-Quintana et al., 2002; Lim et al., 2003b; Ambros et al., 2003; Aravin et al., 2003).”
Computational identification of Drosophila microRNA genes (2003, methodology): “Consideration of nucleotide bias at the 5' end of miRNA (including a propensity to begin with U) may improve predictions [11], although we stress that our algorithms were designed to predict pre-miRNA genes and not mature miRNA sequences themselves.”
Regulation of Flowering Time and Floral Organ Identity by a MicroRNA and Its APETALA2-Like Target Genes Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.016238. (2003, background): “MicroRNAs (miRNAs) are noncoding RNAs of 21 nucleotides in length that have been identified in both animals and plants (Lagos-Quintana et al., 2001, 2002; Lau et al., 2001; Lee and Ambros, 2001; Llave et al., 2002a; Mourelatos et al., 2002; Park et al., 2002; Reinhart et al., 2002).”