The genetic epidemiology of neurodegenerative disease.

By Lars Bertram, Rudolph E. Tanzi. Journal of Clinical Investigation, 2005

632 citations recorded by the source corpus.

Subfields: Molecular Biology, Neurology

View Paper: https://www.semanticscholar.org/paper/98acbf873d6d12f97c2867c7c4baddf6e619a8e0

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Berislav Zlokovic
2. D. Holtzman
3. A. Sagare
4. R. Deane
5. L. Ittner
6. J. Götz
7. Olivier Bodenreider
8. L. Liaudet

In Neurology

1. Berislav Zlokovic
2. A. Sagare
3. D. Holtzman
4. R. Deane
5. J. Götz
6. Olivier Bodenreider
7. L. Ittner
8. C. Iadecola

Citations in the corpus

• Nitric oxide and peroxynitrite in health and disease. (2007, background): “Although various mechanisms, including neuroinflammation, oxidative stress, autoimmunity, a defect in neuronal glutamate transport and glutamate toxicity, neurofilament accumulation, exogenous factors (viruses, toxins), mitochondrial dysfunction, and mutations in the SOD gene were implicated to play”
• Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease (2011, background): “In a small subset of familial Alzheimer's disease (FAD) cases, mutations have been identified in genes that encode the amyloid precursor protein (APP), presenilin-1 (PS1) or PS2 (Ref”
• apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain. (2008, background): “Discussion APOE genotype is the only established genetic risk factor for late-onset sporadic AD with an isoform-specific risk profile of apoE4>apoE3>apoE2 (21, 38, 39).”
• Advancing translational research with the Semantic Web (2007, background): “Increasingly, researchers recognize that Ad, PD, and HD share various features at the clinical [13], neural [14-17], cellular [18-20], and molecular levels [21,22].”
• Human Health Risk Assessment for Aluminium, Aluminium Oxide, and Aluminium Hydroxide (2007, background): “Early onset AD is strongly linked to mutations in 3 genes, with autosomal-dominant inheritance patterns ( Bertram & Tanzi, 2004 ; 2005 ).”
• Advances in multimodal data fusion in neuroimaging: Overview, challenges, and novel orientation (2020, neutral): “Second, a disease, disorder, or lesion may manifest itself in different forms, symptoms, or etiology; or on the other hand, different diseases may share some common symptoms or appearances [2, 3] .”
• Animal models of Alzheimer's disease and frontotemporal dementia (2008, background): “In SAD, various susceptibility genes have been identified, including apolipoprotein E ( APOE”