Nitric oxide and peroxynitrite in health and disease.

By P. Pacher, J. Beckman, L. Liaudet. Physiological Reviews, 2007

6,189 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/b25208941faf189012b4844ce1c4effa0183feba

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Citations in the corpus

The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology (2012, methodology): “One pictorial representation of this situation is provided by Pacher et al [66], and is illustrated in figure 9.”
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics (2007, background): “Putative targets for peroxynitrite include the epidermal growth factor ( EGF ) receptor, the β 1 - and β 2 -adrenoceptors ( ADRB1 and ADRB2 ), platelet/endothelial cell adhesion molecule 1 ( PECAM1 ), insulin receptor substrate 1 ( IRS1 ) and PPARγ (overviewed in Ref”
Reactive nitrogen species in plasma-activated water: generation, chemistry and application in agriculture (2020, background): “Peroxynitrite is able to cross cell membranes and can react with most biological molecules, either by direct oxidation, or indirectly, by decomposing into the highly reactive radicals HO∙ and ∙NO2 [54, 63].”
Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery (2009, background): “Excess peroxynitrite may also induce pericyte contraction by causing mitochondrial dysfunction and intracellular calcium rise or by depolarizing pericytes via inhibition of potassium channel”
Ischemia/Reperfusion (2016, neutral): “interactions, and decreasing the bioavailability of protective NO (222, 243, 290, 292, 463, 615, 649).”
ROS Generation and Antioxidant Defense Systems in Normal and Malignant Cells (2019, background): “CAT can also decompose peroxynitrite (ONOO−) derived from the reaction between NO and H2O2 that prevents hydroxyl radical formation through the NO/peroxynitrite pathway.”
The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state (2015, background): “Immune cells, including macrophages and neutrophils, simultaneously release NO and superoxide into phagocytic vacuoles as a means of generating peroxynitrite to kill endocytosed bacteria [22].”
Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems (2009, background): “Peroxynitrite, O N-O-O , formed in vivo by the reaction of O2 • with free radical nitric oxide by a diffusion-controlled reaction, is an powerful oxidant and nitrating agent [127].”