Ubiquitin and proteasomes: Molecular dissection of autophagy: two ubiquitin-like systems

By Y. Ohsumi. Nature reviews. Molecular cell biology, 2001

1,283 citations recorded by the source corpus.

Subfields: Cell Biology, Epidemiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/94fd8aa791302637fc2885e18bc63f36d484aab2

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Citations in the corpus

An Overview of the Molecular Mechanism of Autophagy (2009, neutral): “6) (Ohsumi 2001).”
Leaf Senescence and Starvation-Induced Chlorosis Are Accelerated by the Disruption of an Arabidopsis Autophagy Gene1 (2002, background): “Effects of sugar on floral transition in Arabidopsis were recently investigated precisely (Ohto et al., 2001).”
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. (2003, background): “In the yeast, Saccharomyces cerevisiae, at least 16 of APG and AUT genes have been identified to be required for autophagosome formation (Klionsky and Ohsumi, 1999; Ohsumi, 2001; Mizushima et al., 2002a).”
Autophagy: a lysosomal degradation pathway with a central role in health and disease. (2009, background): “hagosome formation, the Atg12-Atg5 and the Atg8-phosphatidyl ethanolamine systems [53].”
Autophagy: molecular machinery for self-eating (2005, background): “Two unique ubiquitin-like conjugation systems, Atg8–phosphatidylethanolamine (Atg8–PE) and Atg12–Atg5, are involved in the biogenesis of autophagic vesicles (Figure 4).(52) These conjugation systems are widely conserved in various eukaryotes and have an essential role in autophagy.”
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. (2007, positive): “To identify protein(s) that could interact with LC3, we employed the proteomic approach as described previously (Komatsu et al., 2004) and then identified a unique protein p62 as one of LC3-interacting proteins, in addition to LC3-modifying enzymes (Ohsumi, 2001) (Table S1).”
Processing of ATG8s, Ubiquitin-Like Proteins, and Their Deconjugation by ATG4s Are Essential for Plant Autophagy (2004, background): “ATG4 proteins had a significant but low level of identity with the yeast Atg4 protein (ATG4a-yeast Atg4, 26%; ATG4byeast Atg4, 29%).”
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 (2007, background): “The molecular mechanism underlying autophagy has been extensively researched in the past decade, and the genes participating in this process, denoted ATGs (autophagy- related; Klionsky et al, 2003), were found to be conserved from yeast to man (Ohsumi, 2001; Huang and Klionsky, 2002).”