Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells.
By T. Lapidot, I. Petit. Experimental Hematology, 2002
866 citations recorded by the source corpus.
Subfields: Hematology, Immunology, Oncology
View Paper: https://www.semanticscholar.org/paper/94a7724307b6385ee6a37a7cde5d2f3c935db927
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In Hematology
In Immunology
- Eric G. Pamer
- Stefanie Dimmeler
- Thordur Oskarsson
- N. Serbina
- A. Zeiher
- A. Mildner
- F. Geissmann
- Steffen Jung
In Oncology
Citations in the corpus
- c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. (2004, background): “In addition to the more recent implication of cadherins in stem-cell niche interactions, there is ample evidence to support an important role for integrins in adult stem cell function (Jones and Watt 1993; Pruijt et al. 1998; Whetton and Graham 1999; Hynes 2002; Lapidot and Petit 2002; Velders et al”
- Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. (2009, positive): “Similarly, treatment of mice with the cytokine G-CSF, known to mobilize HSCs (Lapidot and Petit, 2002), also causes dormant HSCs to proliferate efficiently, as the majority of the LRC HSCs lose the BrdU label (Figure 6A).”
- Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis (2007, background): “20070075 1057 Stromal cells are involved in organogenic processes by controlling parenchymal cell functions such as migration, proliferation, diff erentiation, and programmed cell death (1).”
- Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2 (2006, background): “SDF-1 is a chemokine linked to the homing of progenitor stem cells to the bone marro”
- Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells (2003, background): “Maintenance and mobilization of stem cells in the bone marrow is determined by the local microenvironment, which consists of fibroblasts and endothelial cell”