Intracellular Cholesterol Transport

By R. Soccio, J. Breslow. Arteriosclerosis, Thrombosis and Vascular Biology, 2004

658 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Surgery

View Paper: https://www.semanticscholar.org/paper/8d36b8e458475a459ce62fbc95e75579caa13494

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Citations in the corpus

Molecular machinery for non-vesicular trafficking of ceramide (2003, background): “A previous study has shown that the PH domain of human GPBP binds to both phosphatidylinositol-4 monophosphate (PtdIns4P) and phosphatidylinositol-4,5-diphosphate (PtdIns(4,5)P) when the lipids are on artificial phospholipid vesicles, but it probably only binds to PtdIns4P in vivo because its distri”
Cholesterol metabolism and homeostasis in the brain (2015, positive): “, 1997) and NPC2 is an intralumenal component that binds cholesterol (Naureckiene et al., 2000; Soccio and Breslow, 2004).”
Mycobacterial persistence requires the utilization of host cholesterol (2008, background): “This distribution is consistent with the known concentration of intracellular cholesterol in the endoplasmic reticulum in which it is synthesized and the secretory pathway through which it is transported to the plasma membrane (33).”
Role of cholesterol and lipid organization in disease (2005, background): “Cholesterol is synthesized in the ER and delivered to other organelles by a combination of vesicular and non-vesicular transport processe”
Caveolae: From Cell Biology to Animal Physiology (2002, background): “To maintain steady levels intracellularly, peripheral cells can also efflux excess free cholesterol from the exoplasmic leaflet of the plasma membrane to high-density lipoproteins (HDLs) for delivery to the liver, a process known as reverse cholesterol transport (Fielding and Fielding, 1997).”
Cellular cholesterol trafficking and compartmentalization (2008, background): “It has been known for some time that cholesterol is transferred between subcellular membranes by membrane (or vesicular) transport and by non-vesicular mechanism”
The lysosome: from waste bag to potential therapeutic target. (2013, background): “Recycling endosomes, Golgi membranes, and the membranes of ILVs are cholesterol rich, whereas the ER, late endosomes, and lysosomes contain less cholesterol (Maxfield and Wustner, 2002; Möbius et al., 2003).”