Mycobacterial persistence requires the utilization of host cholesterol

By A. Pandey, Christopher M. Sassetti. Proceedings of the National Academy of Sciences of the United States of America, 2008

1,032 citations recorded by the source corpus.

Subfields: Immunology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/6ea842996f8d158c3ead4d0a7897e905663faf82

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. D. Russell

In Infectious Diseases

1. Thomas R. Ioerger
2. Michael A. DeJesus
3. B. Akerley
4. Jennifer E. Griffin
5. Jeffrey D. Gawronski
6. D. Russell
7. Christopher M. Sassetti

Citations in the corpus

• Foamy macrophages and the progression of the human TB granuloma (2009, background): “In addition, Mtb has been shown to be able to metabolize cholestero”
• High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism (2011, methodology): “Disruption of Mce4 function by deleting an essential transmembrane component has been shown to cause specific defects in cholesterol uptake and growth in this carbon source [14].”
• Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence (2008, background): “tb is also critically linked to the acquisition of host cholesterol through the Mce4 transporter system [36].”