Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: A mechanism for cellular human immunodeficiency virus 1 infection
By M. Mack, A. Kleinschmidt, H. Brühl, C. Klier, Peter J. Nelson, J. Cihak, J. Plachý, M. Stangassinger, V. Erfle, D. Schlöndorff. Nature Medicine, 2000
630 citations recorded by the source corpus.
Subfields: Molecular Biology, Virology
View Paper: https://www.semanticscholar.org/paper/8ce0d1affd297fd524038dbd5091da31dc22faf7
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Citations in the corpus
- TCR Activation of Human T Cells Induces the Production of Exosomes Bearing the TCR/CD3/ζ Complex1 (2002, background): “It has also been shown that the chemokine receptor CCR5 may be transferred by microvesicles from CCR5 cells to CCR5 cells (10).”
- Classification, Functions, and Clinical Relevance of Extracellular Vesicles (2012, background): “For instance, transfer of the chemokine receptors CCR5 and CXCR4 makes recipient cells susceptible to entry of HIV (Mack et al., 2000; Rozmyslowicz et al., 2003).”
- Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR (2009, background): “MV-mediated intercellular exchange could include lipids, soluble proteins (6), or nucleic acids (7), but also functional transmembrane proteins (8), chemokine receptors (9), transferrin receptors (3), tissue factor (8, 10), and receptor tyrosine kinases (1, 11), such as HER-2 (12) and EGF receptor (”
- Biological properties of extracellular vesicles and their physiological functions (2015, background): “In addition, EVsmay induce changes in the cell phenotype by transfer to the target cell of functionally active receptors such as CCR5 (93), EGFRvIII (94) or MET (95).”
- Exosome Theranostics: Biology and Translational Medicine (2018, background): “In addition, HIV-1 achieves cell entry by exosome-mediated transfer of chemokine receptor 5 to recipient cells [131].”
- Extracellular Vesicle Heterogeneity: Subpopulations, Isolation Techniques, and Diverse Functions in Cancer Progression (2018, background): “In terms of pathophysiological processes, EVs have established as important players in diseases such as cancer (7), neurodegenerative disease (8), and viral infection (9).”