Cancer stem cells: lessons from leukemia.

By Jean C. Y. Wang, J. Dick. Trends in Cell Biology, 2005

656 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/88eb68bc2d62913ce326688185632810817fe21c

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Citations in the corpus

Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. (2007, background): “However, subsequent experiments indicated that AML LSC, unlike HSC, do not express CD90 (Blair et al., 1997; Miyamoto et al., 2000).”
Cancer stem cells: impact, heterogeneity, and uncertainty. (2012, background): “Thus, hierarchical organization in a cancer does not imply that it originated from normal stem cells, and the cancer stem cell model does not address the cell-of-origin (Wang and Dick, 2005).”
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells (2009, background): “To date, human acute myeloid leukemia (AML) stem cells (LSC) are the most well studied cancer stem cell population (Wang and Dick, 2005).”
Targeting of CD44 eradicates human acute myeloid leukemic stem cells (2006, background): “The leukemic hierarchy is continuously replenished by rare, functionally distinct LSC”
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. (2009, neutral): “Quiescence has been postulated to prevent stem cell exhaustion (Orford and Scadden, 2008) and is thought to help protect stem cells from acquiring mutations leading to their malignant transformation to putative cancer stem cells (Lobo et al., 2007; Park and Gerson, 2005; Wang and Dick, 2005).”
The impact of translocations and gene fusions on cancer causation (2007, background): “In which cells do gene fusions arise? During the past decade, cancer stem cells have attracted much attentio”