Bruchpilot Promotes Active Zone Assembly, Ca2+ Channel Clustering, and Vesicle Release

By R. Kittel, C. Wichmann, Tobias M. Rasse, Wernher Fouquet, Manuela Schmidt, A. Schmid, D. Wagh, Christian Pawlu, R. R. Kellner, K. Willig and 4 more. 2006

796 citations recorded by the source corpus.

Subfields: Cell Biology, Cellular and Molecular Neuroscience, Molecular Biology, Computational Biology & Bioinformatics, Neuroscience

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

Stefan W. Hell

In Cellular and Molecular Neuroscience

In Molecular Biology

In Computational Biology & Bioinformatics

In Neuroscience

Citations in the corpus

Cell-type Specific Labeling of Synapses in vivo through Synaptic Tagging with Recombination (STaR) (2014, background): “T-bars comprise clusters of Bruchpilot (BRP) protein, the single CAST/ERC family member in Drosophila (Fouquet et al., 2009; Kittel et al., 2006; Wagh et al., 2006).”
A guide to super-resolution fluorescence microscopy (2010, methodology): “JCB • VOLUME 190 • NUMBER 2 • 2010 170 STED microscopy has been successfully applied on biological samples (Kittel et al., 2006; Sieber et al., 2006; Willig et al., 2006), for example showing that synaptotagmin remains clustered after synaptic vesicle exocytosis (Willig et al., 2006).”
Development‐based compartmentalization of the Drosophila central brain (2010, background): “This approach allows us to generate a ‘‘protomap’’ of adult compartments at the larval stage and thereby to place the definition of adult compartments into a developmental context.”
Bruchpilot, A Synaptic Active Zone Protein for Anesthesia-Resistant Memory (2011, background): “Importantly, vesicle release at neuromuscular synapses under high-frequency stimulation is still possible, yet not complete, after the elimination of Brp (Kittel et al., 2006).”
Super resolution fluorescence microscopy (2009, background): “For example, synaptotagmin clusters after exocytosis in primary cultured hippocampal neurons (84), the donut-shaped clusters of Drosophila protein Bruchpilot at the neuromuscular synaptic active zone (85), and the size distribution of syntaxin clusters have all been imaged (86,87).”
Far-Field Optical Nanoscopy (2007, background): “In another application, STED microscopy also revealed the ring-like structure of the protein bruchpilot at synaptic active zones in the drosophila neuromuscular junction [90].”
Different classes of input and output neurons reveal new features in microglomeruli of the adult Drosophila mushroom body calyx (2012, background): “pilot) is a component of the platform of T-bar ribbons in the larval neuromuscular junction (Kittel et al., 2006; Fouquet et al., 2009) as well as in the adult fly’s brain, for”
Multiple roles of calcium ions in the regulation of neurotransmitter release. (2008, background): “In other words, slowly releasing vesicles may be perfectly release competent with respect to their intrinsic Ca sensitivity, but located too far away from Ca channels (which are known to be clustered at active zones; Roberts et al., 1990; Adler et al., 1991; Llinas et al., 1992; Haydon et al., 1994;”