The molecular understanding of osteoclast differentiation.

By M. Asagiri, Hiroshi Takayanagi. Bone, 2007

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Bioactive calcium phosphate materials and applications in bone regeneration (2019, background): “Furthermore, calcium ions regulate the formation and the resorptive functions of osteoclasts [33, 34].”
Current Understanding of RANK Signaling in Osteoclast Differentiation and Maturation (2017, background): “Osteoclasts are bone-resorbing multinucleated cells that originate from hematopoietic precursors that are formed in the bone marrow (Asagiri and Takayanagi, 2007; Boyle et al., 2003; Karsenty and Wagner, 2002; Teitelbaum, 2000).”
Cysteine cathepsins: From structure, function and regulation to new frontiers (2011, background): “bone resorption has been unambiguously documented in mice and humans [23].”
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems (2007, background): “and receptor activator of nuclear factor-κB ( NF-κB ) ligand ( RANKL ; also known as TNFSF11), a tumour-necrosis factor (TNF)-family cytokin”
Denosumab and bisphosphonates: different mechanisms of action and effects. (2011, background): “an absolute requirement for commitment to and progression of early precursors along the osteoclast lineage [17–19].”