Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss.

By R. Cancello, C. Henegar, N. Viguerie, S. Taleb, C. Poitou, C. Rouault, M. Coupaye, V. Pelloux, D. Hugol, J. Bouillot and 9 more. Diabetes, 2005

1,199 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Epidemiology, Physiology

View Paper: https://www.semanticscholar.org/paper/85070b30cf3b56a7806366873c5cc554c9d5e6a4

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In Cardiology and Cardiovascular Medicine

In Epidemiology

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Citations in the corpus

Increased Number of Islet-Associated Macrophages in Type 2 Diabetes (2007, background): “After screening human islet, mouse islet, and cell line preparations, we concentrated on the regulation of IL-6, IL-8, G-CSF, interferon-inducible protein 10 (IP-10), MIP1 , MCP-1, and chemokine KC in the rodents (all known to be elevated in type 2 diabetic and obese subjects [1,2,24]).”
Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity. (2016, background): “, after bariatric surgery-induced 20% weight loss that has been associated with decreased gene expression of pro-inflammatory cytokines and macrophage number in adipose tissue of people with obesity (Bradley et al., 2012; Cancello et al., 2005; Moschen et al., 2010).”
Obesity induces a phenotypic switch in adipose tissue macrophage polarization. (2007, background): “Moreover, weight loss leads to a reduction in both inflammatory markers and ATM content (4, 7).”
Adipokines: the missing link between insulin resistance and obesity. (2008, background): “[100] Cancello R, Henegar C, Viguerie N, Taleb S, Rouault C, Coupaye M, et al.”
Fibrosis and Adipose Tissue Dysfunction (2013, background): “As such, the gene expression of HIF1a is upregulated in subcutaneous AT of obese subjects (Cancello et al., 2005).”
Role of neuroinflammation in neurodegenerative diseases (Review) (2016, neutral): “Anxiety was alleviated with the reduction of inflammation following the surgical removal of fat tissue (44).”
Immune System to Brain Signaling: Neuropsychopharmacological Implications (2011, background): “, decreased pro-inflammatory factors and increased antiinflammatory molecules) and regulate inflammation-related genes in white adipose tissue (Bastard et al., 2000; Clement et al., 2004; Cancello et al., 2005; Forsythe et al., 2008).”
Adipocyte Death, Adipose Tissue Remodeling, and Obesity Complications (2007, background): “CCR2 M s expressing the M differentiation marker F4/80 and CD11c, a dendritic cell (DC) marker (13) upregulated in M foam cells (14), were recently reported to infiltrate AT of obese mice and were distinguished from noninflammatory resident ATM s (F4/ 80 /CCR2 /CD11c ) isolated from nonobese mice (1”
Increased Infiltration of Macrophages in Omental Adipose Tissue Is Associated With Marked Hepatic Lesions in Morbid Human Obesity (2006, background): “Because adipocyte hypertrophy is a factor determining WAT macrophage infiltration (3,6), we assessed the relationship between adipose cell diameter and the percentage of macrophages in omental and subcutaneous WAT.”