Neuropathologic features of amnestic mild cognitive impairment.

By Ronald C. Petersen, Joseph E. Parisi, Dennis W. Dickson, Kris A. Johnson, David S. Knopman, Brad Boeve, Gregory A. Jicha, R. Ivnik, Glenn E. Smith, E. Tangalos and 2 more. Archives of Neurology, 2006

625 citations recorded by the source corpus.

Subfields: Physiology, Psychiatry and Mental health, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/8497a1668076cb0b91669f0fdd8d089011c9e880

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Citations in the corpus

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. (2008, background): “The clinical diagnosis of patients with amnestic MCI, which can be considered an early, prodromal form of AD (25), was confirmed by the presence of mild AD pathology postmortem (data not shown).”
Enrichment Effects on Adult Cognitive Development (2008, neutral): “preclinical symptoms of a dementing illness (Albert, Blacker, Moss, Tanzi, & McArdle, 2007; Lopez, Li, Shing, & Lindenberger, 2007; Petersen et al., 2006).”
Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. (2007, background): “MCI is considered by many to represent the earliest clinical manifestation of an evolving dementing illness, which is usually Alzheimer’s disease (Petersen et al., 1999, 2001a, 2006; Petersen, 2000; Jicha et al., 2006).”
Pathology of Neurodegenerative Diseases. (2017, background): “However, recent studies have questioned the specificity of this clinical syndrome, as it is associated with mild cognitive impairment (Petersen et al. 2006) and its main effect is to modify the phenotype of the disorder in which it occurs (Josephs et al. 2008c).”
Mild cognitive impairment: ten years later. (2009, background): “Two studies from the Mayo Clinic published in the Archives of Neurology shed additional light on these participants.(55,56) One study evaluated participants who died while their clinical classification was MCI and found that most had a low probability of having the neuropathological features of AD a”
Introduction to Revised Criteria for the Diagnosis of Alzheimer’s Disease: National Institute on Aging and the Alzheimer Association Workgroups (2011, background): “[16] Petersen RC, Parisi JE, Dickson DW, Johnson KA, Knopman DS,”
The Episodic Memory System: Neurocircuitry and Disorders (2009, positive): “A recent community-based study of the neuropathology of amnesic MCI identified hippocampal sclerosis in 3 of 15 patients who died (Petersen et al, 2006).”
Comparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's disease (2017, background): “The transition from normal aging to preclinical AD is characterized by an increase of tau tangles within and spread out of the medial temporal lobe to limbic areas (Braak stage III-IV; see e.g. Petersen et al., 2006).”
The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease (2011, methodology): “Nevertheless, similar to the criteria proposed by the International Working Group of Dubois et al [7], these criteria assume that it is possible to identify those individuals with AD pathophysiological processes as the likely primary cause of their progressive cognitive dysfunction [8–10].”
Neural Correlates of Alzheimer's Disease and Mild Cognitive Impairment: A Systematic and Quantitative Meta-Analysis involving 1,351 Patients (2009, neutral): “All rights reserved. doi:10.1016/j.neuroimage.2009.05.037 Contents lists available at ScienceDirect”
Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future (2023, background): “Aβ promoted the phosphorylation and activation of Fyn kinase, which further migrated into dendritic spines, leading to synaptic impariment.(141,142) Tau protein mediated Aβ toxicity by interacting with Fyn kinase via its amino-terminal projection domain (PD).”
The Neuropathology of Probable Alzheimer's Disease and Mild Cognitive Impairment (2009, result): “Prior studies had relatively few persons with MCI, with the largest study including 57 subjects(16); furthermore, they either included both amnestic and nonamnestic MCI as a single group, or were restricted to amnestic MCI.(12,13) Two additional studies focused on the neuropathology of MCI after con”