Chromatin in pluripotent embryonic stem cells and differentiation

By Eran Meshorer, Tom Misteli. Nature reviews. Molecular cell biology, 2006

741 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/82ab15c2281b0b6a757277bae4f04c019bdae2f6

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Citations in the corpus

Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. (2007, background): “It has been suggested that this potential is related to an unusual chromatin structure or to specific histone modifications (Azuara et al., 2006; Lee et al., 2004; Martens et al., 2005; Meshorer and Misteli, 2006).”
Polycomb silencers control cell fate, development and cancer (2006, background): “Emerging data point to a key role for an epigenetic regulation of these fundamental processe”
A chromatin landmark and transcription initiation at most promoters in human cells. (2007, background): “ES cells possess unique properties, including pluripotency, self-renewal, and hyperdynamic chromatin (Meshorer and Misteli, 2006).”
Global transcription in pluripotent embryonic stem cells. (2008, background): “transcriptionally hyperactive and express large regions of the genome, possibly indiscriminately and at low levels (Meshorer and Misteli, 2006).”
Pluripotency: Toward a gold standard for human ES and iPS cells (2009, background): “In addition, undifferentiated pluripotent cells have a distinctive nuclear architecture (lamina, nuclear speckles and heterochromatin domains) as well as chromatin structure (Meshorer and Misteli, 2006).”
Distinct Epigenomic Landscapes of Pluripotent and Lineage-committed Human Cells (2010, background): “In stem cells, the epigenome is highly malleable and responsive (Meshorer and Misteli, 2006), unlike that of somatic cells.”
Hydrodynamic stretching of single cells for large population mechanical phenotyping (2012, background): “In the process of differentiation, cells gain regions of condensed heterochromatin with which nucleoproteins are more closely associated, whereas these proteins are dynamically associated with a loose chromatin structure in undifferentiated cells (39).”
CTCF-Mediated Functional Chromatin Interactome in Pluripotent Cells (2011, background): “Its spatial distribution and temporal regulation are crucial for cell identity and cell fate decisio”