Global transcription in pluripotent embryonic stem cells.
By S. Efroni, R. Duttagupta, Jill Cheng, Hesam Dehghani, Daniel J. Hoeppner, Chandravanu Dash, D. Bazett-Jones, S. L. Le Grice, R. McKay, K. Buetow and 3 more. Cell Stem Cell, 2008
720 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/3ea55746e71747edb555d3939d6a0a0378ad703b
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In Molecular Biology
- John S. Mattick
- Marcel E. Dinger
- Tim R. Mercer
- Ken C. Pang
- Paulo P. Amaral
- José C. R. Silva
- Jesús Gil
- B. van Steensel
Citations in the corpus
- Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation. (2008, background): “Moreover, it has been recently shown that the majority of the chromatin is open in undifferentiated ES cells and that there is widespread low-level transcription of both protein-coding and non-coding sequences, which is progressively restricted as the cells undergo differentiation (Efroni et al. 200”
- Senescence impairs successful reprogramming to pluripotent stem cells. (2009, background): “These proteins are important to maintain chromatin in an open state and contribute to global transcriptional activity (Efroni et al., 2008).”
- Molecular maps of the reorganization of genome – nuclear lamina interactions during differentiation (2010, background): “…ESCs some structural chromatin proteins are less stably bound (Meshorer et al., 2006), intergenic transcription has been reported to be more widespread (Efroni et al., 2008), and replication timing domains appear somewhat more fragmented compared to differentiated cells (Hiratani et al., 2008).”