Natural killer cells and dendritic cells: rendezvous in abused tissues

By A. Moretta. Nature reviews. Immunology, 2002

731 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/7b88f16b10df7811fee5fac5d8940d4fa1e86619

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In Immunology

Citations in the corpus

Unravelling natural killer cell function: triggering and inhibitory human NK receptors (2004, background): “On the other hand, the ‘on’ signal can be readily detected when NK cells interact with target cells that lack MHC class I molecules.”
Cutting Edge: Murine Dendritic Cells Require IL-15Rα to Prime NK Cells1 (2004, background): “In addition, IL-15R is directly involved in the priming of NK cells by DCs, providing a molecular mechanism for this process (29, 30).”
Induced recruitment of NK cells to lymph nodes provides IFN-γ for TH1 priming (2004, background): “Evidence from both human and mouse studies suggests that NK cells may also participate in adaptive immune responses by modulating DC function or by producing IFN-&gamma”
The Abundant NK Cells in Human Secondary Lymphoid Tissues Require Activation to Express Killer Cell Ig-Like Receptors and Become Cytolytic1 (2004, background): “Cytolytic NK cells might control infected and tumor cells infiltrating secondary lymphoid organs, as well as edit APCs such as dendritic cells.”
Inflammation and necrosis promote tumour growth (2004, background): “— or for cells that have diminished expression of MHC class I molecule”
Dendritic cells prime natural killer cells by trans-presenting interleukin 15. (2007, background): “It has been proposed that functionally relevant interactions between NK cells and DCs occur in peripheral tissues (Moretta, 2002).”
MHC class I molecules and kirs in human history, health and survival (2005, background): “; they kill infected cells, secrete inflammatory cytokines (notably, IFN-γ) and interact with DCs to determine if and when an adaptive immune response should commenc”
Mesenchymal stem cells in health and disease (2008, background): “Natural killer (NK) cells are important effector cells of innate immunity and they have a key role in antiviral and anti-tumour immune responses owing to their cytolytic activity and production of pro-inflammatory cytokine”