Cutting Edge: Murine Dendritic Cells Require IL-15Rα to Prime NK Cells1

By R. Koka, Patrick R. Burkett, Marcia Chien, Sophia Chai, D. Boone, A. Ma. Journal of Immunology, 2004

195 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/6dbfc56ae483813e6dd09169b316f6d0c235a5c7

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In Immunology

1. Chao Yang
2. A. Diefenbach
3. Monica S. Thakar
4. Alex M. Abel
5. S. Malarkannan

Citations in the corpus

• Natural Killer Cells: Development, Maturation, and Clinical Utilization (2018, background): “The trans-presentation of IL-15 by IL-15Rα to IL-15Rα/IL-2Rβ/IL-2Rγ complex on NK cells initiates multiple cellular tasks including proliferation and transcriptional reprogramming (81, 174).”
• Dendritic cells prime natural killer cells by trans-presenting interleukin 15. (2007, methodology): “These data demonstrate that TLR stimulation of BMDCs induces type I IFN production and that the response to the type I IFN signal by DCs (but not NK cells) is required for the priming of NK cells (Figures 5, 6C, and 6D).”