Mesenchymal stem cells in health and disease

By Antonio Uccelli, L. Moretta, Vito Pistoia. Nature reviews. Immunology, 2008

3,631 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/25f530e17044cb60961794dab4ca6cf3bc29aad0

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Citations in the corpus

Bone substitutes in orthopaedic surgery: from basic science to clinical practice (2014, background): “The proposed use of MSCs in orthopedic surgery comes also from their immunomodulatory properties, that make them potentially suitable for allogenic transplantation [185].”
Immunobiology of mesenchymal stem cells (2013, background): “MSCs are involved in many physiological and pathological processes, including cellular homeostasis maintenance, aging, tissue damage and inflammatory diseases.(1,17,18)”
Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis (2015, background): “…the expression pattern for pancreatic and gastric CSCs (155, 156), because CD24 is a canonical epithelial marker, and CD44 is a mesenchymal stem cell one (157, 158), and CD24 + CD44 + expression pattern overlaps with high levels of P-cadherin, another proposed marker of partial EMT phenotype (92).”
Biomaterial based modulation of macrophage polarization: A review and suggested design principles (2015, background): “MSC/macrophage cross-talk Mesenchymal stem cells or multipotent stromal cells (MSCs) are adult stem cells that are found in tissues such as the bone marrow and can differentiate toward a multitude of lineages that constitute tissues including fat, bone, cartilage, muscle and skin, making them popula”
Mesenchymal stem cell-macrophage crosstalk and bone healing (2018, background): “The exact definition of the MSC remains controversial, but the term is generally used to describe a population of stem cells that resides in the peri-vascular niche of most tissues, and with the ability to differentiate into mesodermal tissues, such as bone and cartilage [15, 16].”
Risk factors in the development of stem cell therapy (2011, methodology): “In addition, MSCs have been shown to suppress lymphocyte proliferation to allogenic or xenogenic antigens [81,82,84] leading to acceptation of allo/xenotrans-plants in animal models [90].”
Mesenchymal stromal cells: new directions. (2012, background): “There have been several comprehensive recent reviews on MSCs (Uccelli et al., 2008; Bianco et al., 2008; Tolar et al., 2010; Ranganath et al., 2012).”
Mesenchymal Stem Cell Exosomes Induce Proliferation and Migration of Normal and Chronic Wound Fibroblasts, and Enhance Angiogenesis In Vitro (2015, background): “In addition to their multipotent potential, MSCs have an extensive ex vivo expansion capacity and can regulate immune and inflammatory processes, making these cells attractive for the treatment of numerous disorders [12].”
Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury. (2011, background): “Bone marrow (BM) mesenchymal stem cells (MSCs) were extensively investigated for their reparative, regenerative and immunomodulatory properties [1,2].”
Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6 (2009, background): “…n = 3 or 4 mice in each group; ***p < 0.0001 compared to MI controls; N.S., not significant compared to MI controls; *p < 0.05 for MI + MSCs versus MI + rhTSG-6. lez-Rey et al., 2009; Sasportas et al., 2009), apparently because of the immune modulatory effects of the cells (Uccelli et al., 2008).”