Delirium in an intensive care unit: a study of risk factors

By M. Dubois, N. Bergeron, M. Dumont, S. Dial, Y. Skrobik. Intensive Care Medicine, 2001

638 citations recorded by the source corpus.

Subfields: Critical Care and Intensive Care Medicine, Radiological and Ultrasound Technology

View Paper: https://www.semanticscholar.org/paper/76a66a29d06b9a8361cc7cc62554be3bbadf09b4

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In Critical Care and Intensive Care Medicine

Citations in the corpus

Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit (2013, background): “Some moderate-quality studies reported a strong relationship between benzodiazepine use and the development of delirium (332, 405), while others found no significant relationship (322, 368, 401-404).”
Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. (2004, background): “Numerous risk factors for delirium have been identified, including preexisting cognitive impairment; advanced age; use of psychoactive drugs; mechanical ventilation; untreated pain; and a variety of medical conditions such as heart failure, prolonged immobilization, abnormal blood pressure, anemia, ”
Long-Term Cognitive Impairment after Critical Illness (2013, neutral): “Other surgical procedure ‡‡ 82 (10) 65 (14)”
Costs associated with delirium in mechanically ventilated patients* (2004, background): “the incidence of delirium from a less severely ill ICU cohort in which delirium occurred in only 19% of patients (46), the estimated annual costs would still be in the range of $1.”
Lorazepam Is an Independent Risk Factor for Transitioning to Delirium in Intensive Care Unit Patients (2006, background): “Similarly, Dubois et al.13 have shown that opiates (morphine and meperidine) administered either intravenously or epidurally may be associated with the development of Anesthesiology, V 104, No 1, Jan 2006 delirium in medical/surgical ICU patients.”
Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS). (2003, background): “Only recently has the ICU community begun to focus on delirium as an essential element of patient comfort and outcome.(8,50,51) Importantly, a key feature of delirium is the presence or absence of inattention, which can be measured in part by the ability of a person to maintain eye contact.”
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. (2007, background): “Chronic obstructive pulmonary disease 2 (4) 2 (4) .”
Incidence, risk factors and consequences of ICU delirium (2006, methodology): “APACHE II score, Glasgow Coma Scale (GCS), and selected laboratory values [10] were recorded.”
Days of delirium are associated with 1-year mortality in an older intensive care unit population. (2009, background): “Several studies have documented the risk of delirium occurrence with the use of psychoactive medications in the ICU (3, 12, 30, 39).”
Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). (2001, neutral): “65 28 100 (86-100) 100 (85-100) 100 (16-100) 83 (16-100)”
Sedation in the intensive care setting (2012, positive): “Clinical Pharmacology: Advances and Applications 2012:4 positively associated with increased risk for delirium.(22,23) Thus, providing systemic analgesia with opioids to patients in pain may be protective of acute brain dysfunction, while excessive administration to achieve sedation may be detriment”