Role of membranes in the activities of antimicrobial cationic peptides.

By Robert E. W. Hancock, A. Rozek. FEMS Microbiology Letters, 2002

607 citations recorded by the source corpus.

Subfields: Microbiology, Molecular Biology, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/760fee0b1a1e09582ddfacce33ed63f041cc4be8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Microbiology

1. Robert E. W. Hancock
2. Guangshun Wang
3. Zhe Wang
4. M. Malmsten
5. A. Schmidtchen
6. Mukesh Pasupuleti
7. H. Jenssen
8. P. Hamill

In Molecular Biology

1. James J. Collins
2. Robert E. W. Hancock
3. Guangshun Wang
4. Zhe Wang
5. Michael A. Kohanski
6. M. Malmsten
7. A. Schmidtchen
8. Mukesh Pasupuleti

In Organic Chemistry

1. Robert E. W. Hancock
2. Christopher D. Fjell

Citations in the corpus

• APD: the Antimicrobial Peptide Database (2004, background): “It is generally accepted that these cationic peptides selectively interact with anionic bacterial membranes (4,5) although different mechanisms may be used by different peptides under different conditions for killing (6).”
• Antimicrobial peptides: key components of the innate immune system (2012, background): “It is predicted that each species could contain a wide variety of AMPs (Hancock and Rozek, 2002), describing all them is beyond the scope of any review.”
• The relationship between peptide structure and antibacterial activity. (2003, background): “While this review will briefly discuss mechanisms, more detailed reviews can be consulted [13,31,33,42,75,87] .”
• Cationic host defense (antimicrobial) peptides. (2006, background): “Most active antimicrobial peptides are able to interact with bacterial membranes, as described by four separate models [2,5].”
• Peptide Antimicrobial Agents (2006, background): “It is well understood that regardless of their actual target of action, all antibacterial cationic peptides must interact with the bacterial cytoplasmic membrane (92).”
• Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic-resistant superbugs. (2009, background): “Cationic antimicrobial peptides always interact with membranes as part of their mechanism of action (10).”
• How antibiotics kill bacteria: from targets to networks (2010, background): “Antimicrobial peptides are short cationic peptides that are thought to kill through interactions with the membrane that result in pore formatio”