The relationship between peptide structure and antibacterial activity.

By J. Powers, Robert E. W. Hancock. Peptides, 2003

926 citations recorded by the source corpus.

Subfields: Microbiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a9d5abfe2cdefc2b4cdfce6083c13e7661e7d155

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In Microbiology

In Molecular Biology

Citations in the corpus

The Roles of Antimicrobial Peptides in Innate Host Defense (2009, background): “AMPs are traditionally broken into four structural classes: linear, beta-sheet, loop, and extended structures [33].”
Antimicrobial peptides: an overview of a promising class of therapeutics (2007, background): “These studies have indicated that all AMPs interact with membranes and tend to divide peptides into two mechanistic classes: 1) membrane disruptive (barrel stave, toroidal, carpet and micellar aggregate models) and 2) non-membrane disruptive (intracellular targets) [45].”
Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation (2008, background): “to have various targets within the bacterial cell, including cell membranes, DNA, RNA, and cellular proteins, among others (37).”
Designing antimicrobial peptides: form follows function (2011, background): “These peptides have very different folds, which suggests that elements of their secondary structure can be used as a means for classification 68 .”
Antimicrobial Activities and Structures of Two Linear Cationic Peptide Families with Various Amphipathic β-Sheet and α-Helical Potentials (2005, background): “These classes contain well over 500 naturally occurring cationic antimicrobial peptides, and their structural and functional properties have recently been reviewed (2, 27).”
Antimicrobial Peptides: An Emerging Category of Therapeutic Agents (2016, background): “One of the best studied peptides in this group is indolicidin, produced by bovine leukocytes (Powers and Hancock, 2003).”
Antimicrobial Peptides (2013, background): “Among these structural groups, α-helix and β-sheet structures are more common [41]; and α-helical peptides are the most studied AMPs to date.”
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? (2005, background): “Although many relationships between peptide structure and antibacterial activity have been describe”
Peptide Antimicrobial Agents (2006, background): “(201), which hypothesizes that highly charged cationic peptides”