A whole-genome assembly of Drosophila.

By Eugene W. Myers, Granger G. Sutton, Arthur L. Delcher, I. Dew, Daniel P. Fasulo, M. Flanigan, S. Kravitz, C. Mobarry, Knut Reinert, K. Remington and 19 more. Science, 2000

1,654 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/722179d4f64c606c705c71db7b1c03f8c48d6a46

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Citations in the corpus

FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations (2014, neutral): “melanogaster was first released in 2000 (8,9).”
Genomics of the fungal kingdom: Insights into eukaryotic biology (2005, background): “Advances in assembly algorithms (Myers et al. 2000; Aparicio et al. 2002; Batzoglou et al. 2002; Jaffe et al. 2003; Mullikin and Ning 2003) and the inclusion of end sequences from large insert clones (e.”
SeqAn An efficient, generic C++ library for sequence analysis (2008, background): “The assemblies of large eucaryotic genomes like Drosophila melanogaster [5], human [1], and mouse [6] are prime examples where algorithm research was successfully applied to a biological problem.”
A whole-genome assembly of the domestic cow, Bos taurus (2009, methodology): “To avoid this problem, we modified the Celera Assembler (CelAsm) program [ 13 ] to compute coverage and repeat statistics using only WGS reads.”
Phased Diploid Genome Assembly with Single Molecule Real-Time Sequencing (2016, background): “If the minority SNP percentage is small, it means there could be a small number of (1) local phasing errors, (2) incorrect SNP calls, and/or (3) assembly base errors but no major haplotype switching errors.”
Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads (2016, background): “3), both of which are modern implementations of the Celera Assembler designed for high-error long reads[2,3,46].”
Assembly Algorithms for Next-Generation Sequencing Data (2010, neutral): “Unitigs are mini-assemblies that are, ideally, uncontested by overlaps to reads in other unitigs [37].”
Reducing storage requirements for biological sequence comparison (2004, methodology): “Sequence comparison is a fundamental tool of computational biology, used in applications such as overlap determination in genome sequence assembly (Myers et al., 2000; Batzoglou et al., 2002; Ewing and Green, 1994, http://www.genome.washington.edu or http://www.phrap.org), as well as gene finding…”