Genomics of the fungal kingdom: Insights into eukaryotic biology
By James E. Galagan, Matthew R. Henn, Li‐Jun Ma, Christina A. Cuomo, Bruce W. Birren. 2005
150 citations recorded by the source corpus.
The last decade has witnessed a revolution in the genomics of the fungal kingdom. Since the sequencing of the first fungus in 1996, the number of available fungal genome sequences has increased by an order of magnitude. Over 40 complete fungal genomes have been publicly released with an equal number currently being sequenced—representing the widest sampling of genomes from any eukaryotic kingdom. Moreover, many of these sequenced species form clusters of related organisms designed to enable comparative studies. These data provide an unparalleled opportunity to study the biology and evolution of this medically, industrially, and environmentally important kingdom. In addition, fungi also serve as model organisms for all eukaryotes. The available fungal genomic resource, coupled with the experimental tractability of the fungi, is accelerating research into the fundamental aspects of eukaryotic biology. We provide here an overview of available fungal genomes and highlight some of the biological insights that have been derived through their analysis. We also discuss insights into the fundamental cellular biology shared between fungi and other eukaryotic organisms.
Subfields: Cell Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/595da3521a521e615a30bfd5368dae96cfbc7faa
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Citations in the corpus
- Large-scale generation and analysis of filamentous fungal DNA barcodes boosts coverage for kingdom fungi and reveals thresholds for fungal species and higher taxon delimitation (2018, background): “They have been shown to be divergent, even between the members of the same genus (Galagan et al. 2005), and dynamic in nature (Dujon et al.”