The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease.

By S. Collins, P. Bercik. Gastroenterology, 2009

596 citations recorded by the source corpus.

Subfields: Gastroenterology, Molecular Biology, Pharmacy

View Paper: https://www.semanticscholar.org/paper/6e245981347a4249360bfc9e15888d14c083d72f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Gastroenterology

1. J. Cryan
2. Ted G. Dinan
3. C. Stanton
4. G. Clarke
5. P. Kennedy
6. J. Foster

In Molecular Biology

1. J. Cryan
2. Ted G. Dinan
3. C. Stanton
4. Rosa Krajmalnik-Brown
5. J. Adams
6. B. B. Finlay
7. L. Antunes
8. I. Sekirov

In Pharmacy

1. J. Cryan
2. Ted G. Dinan
3. C. Stanton
4. G. Clarke
5. S. Mazmanian
6. P. Kennedy

Citations in the corpus

• Intestinal microbiota in functional bowel disorders: a Rome foundation report (2012, background): “Data in rodents suggest the existence of a bidirectional interplay between the brain and gut microbiota.(144) In addition, the existence of systemic immune responses to microbial luminal antigens (antiflagellin antibodies)(148) provides initial evidence that microbial homeostasis may be perturbed be”
• Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children (2013, background): “In addition, considering the potential interactions between intestinal microbes and the central nervous system [10], abnormal intestinal flora may be associated not only with GI problems but also with ASD-related behavioral symptoms.”
• Gut microbiota in health and disease. (2010, background): “These observations prompted many to hypothesize on the role of the microbiota in the regulation of mood and behavior, and their contribution to the pathophysiology of mood disorders (47, 74, 211, 246).”
• The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems (2015, background): “The current working hypothesis in IBS is that an abnormal microbiota activates mucosal innate immune responses, which increase epithelial permeability, activate nociceptive sensory pathways inducing visceral pain, and dysregulates the enteric nervous system [62,63].”
• Psychobiotics: a novel class of psychotropic. (2013, background): “It has been shown that the plasma serotonin levels of conventional mice are significantly higher than germ free (GF) mice, who have no intestinal microbiota (13), demonstrating the capacity of the microbiota to”
• Exposure to a Social Stressor Alters the Structure of the Intestinal Microbiota: Implications for Stressor-Induced Immunomodulation (2010, result): “This is consistent with findings in patients with functional and inflammatory bowel disease that have frequent psychiatric co-morbidity and alterations in the intestinal microbiota (Collins and Bercik, 2009).”