Human NK cell education by inhibitory receptors for MHC class I.

By Nicolas Anfossi, P. André, S. Guia, C. Falk, Sophie Roetynck, C. A. Stewart, V. Breso, C. Frassati, D. Reviron, D. Middleton and 3 more. Immunity, 2006

1,253 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/6c682444605c80ca3f6a9377e7ef54cd89e3f29a

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In Immunology

1. A. Steinle
2. I. Waldhauer
3. É. Vivier
4. S. Ugolini
5. M. Caligiuri
6. Peter Parham
7. M. Peterson
8. S. Rajagopalan

Citations in the corpus

• Functions of natural killer cells (2008, background): “These CD56 dim NK cell are cytotoxic and produce IFN-γ upon interaction with tumor cells in vitro”
• IL-15 trans-presentation promotes human NK cell development and differentiation in vivo (2009, neutral): “…infl uences the functional maturation of developing NK cells, as NK cells expressing at least one KIR-recognizing self – MHC-I have a lower threshold of activation and appear more functional than NK cells expressing no KIRs or those only expressing KIRs recognizing non-self – MHC-I ligands ( 6 ).”
• NK cells and cancer immunosurveillance (2008, background): “NK cells that do not express at least one inhibitory receptor matching the own MHC class I outfit are hyporesponsive (Kim et al., 2005; Anfossi et al., 2006).”
• Dendritic cells prime natural killer cells by trans-presenting interleukin 15. (2007, background): “Together with data from other groups demonstrating that NK cells undergo an education process that has been compared by some to ‘‘positive selection’’ of T cells (Anfossi et al., 2006; Fernandez et al., 2005; Kim et al., 2005), and a recent report indicating that NK cells are capable of immunologica”
• Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1 (2007, result): “This model is consistent with recent studies implicating inhibitory receptors for MHC class I in the education and eventual killing capacity of NK cell”
• Controlling NK Cell Responses: Integration of Signals for Activation and Inhibition (2013, background): “NK cells that lack ITIM-bearing inhibitory receptors for self-MHC-I and NK cells from hosts that lack MHC-I ligands for ITIM-bearing inhibitory receptors have a reduced responsiveness to activation signals, such as cross-linking of an activation receptor or stimulation by sensitive target cells (5, ”
• The broad spectrum of human natural killer cell diversity (2017, background): “Nonetheless, CD56 cNK cells can produce abundant cytokines upon direct engagement with target cells that express receptor-triggering ligands and/or are coated with antibodies that can trigger CD16 (Anfossi et al., 2006; Björkström et al., 2010; Strauss-Albee et al., 2015).”