The N Terminus of Bacterial Elongation Factor Tu Elicits Innate Immunity in Arabidopsis Plants

By Gernot Kunze, Cyril Zipfel, S. Robatzek, Karsten Niehaus, T. Boller, G. Felix. The Plant Cell Online, 2004

941 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/69e6e803f9e9e85d08e63c918e0d84bb52297007

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Citations in the corpus

Callose deposition: a multifaceted plant defense response. (2011, background): “Examples of bacterial PAMPs are the 22–amino acid sequence of the con- served N-terminal part of flagellin (Gomez-Gomez and Boller 2000) and the bacterial elongation factor EF-Tu (Elf18) (Kunze et al. 2004).”
The Arabidopsis Leucine-Rich Repeat Receptor–Like Kinases BAK1/SERK3 and BKK1/SERK4 Are Required for Innate Immunity to Hemibiotrophic and Biotrophic Pathogens[W] (2011, background): “An increase in ethylene biosynthesis can be measured in leaves within 2 h of treatment with flg22 or elf18 (Felix et al., 1999; Kunze et al., 2004).”
Role of stomata in plant innate immunity and foliar bacterial diseases. (2008, background): “In addition to flagellin, other highly conserved bacterial molecules such as RNA-binding motif RNP-1, elongation factor Tu, and LPS, also elicit hallmark responses of PAMP-induced innate immune response (33,63,120, 122).”
Signaling in Plant-Microbe Interactions (2013, background): “The PRRs such as EFR and FLS2 rapidly forms complex with BAK1 upon treatment of EF-Tu and flg22.”
Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis. (2006, background): “Since the responses to elf26 and flg22 are almost identical (Kunze et al. 2004), FLS2-GFP internalization is not due to cellular changes such as ion fluxes or the formation of ROS induced by PAMPs in general but strictly depends on binding of the ligand.”
Receptor-like cytoplasmic kinases integrate signaling from multiple plant immune receptors and are targeted by a Pseudomonas syringae effector. (2010, background): “Arabidopsis plants exposed to various PAMPs deposit callose at the cell wall and develop a rapid oxidative burst exemplified by the accumulation of H2O2 (Felix et al., 1999; Gómez-Gómez et al., 1999; Kunze et al., 2004; Miya et al., 2007).”
Pattern-recognition receptors in plant innate immunity. (2008, positive): “com EF-Tu: an unexpected PAMP? Elongation factor Tu (EF-Tu) is the most abundant bacterial protein and is recognised as a PAMP in Arabidopsis and other members of the family Brassicaceae [26].”
The Arabidopsis Receptor Kinase FLS2 Binds flg22 and Determines the Specificity of Flagellin Perception[W] (2005, methodology): “synthesized as described previously (Kunze et al., 2004).”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “This PRR has only been found in members of the Brassicaceae family, indicating that EF-Tu recognition has been acquired only recently during evolution (Kunze et al., 2004).”
Roles of Protein Synthesis Elongation Factor EF-Tu in Heat Tolerance in Plants (2012, background): “The innate immunity of the plant cells induces an oxidative burst and ethylene production and results in resistance to subsequent infection of pathogenic microbes [57, 58].”
The Apoplastic Oxidative Burst Peroxidase in Arabidopsis Is a Major Component of Pattern-Triggered Immunity[W][OA] (2012, methodology): “The microbial elicitors included the synthetic peptides Flg22 (Felix et al., 1999) and Elf26 (Kunze et al., 2004), which were synthesized by the Massachusetts General Hospital Peptide Synthesis and Sequencing Core Facility, Boston, Massachusetts, and used at concentrations of 0.5 mM unless…”