Myocardial Cell Death in Human Diabetes
By A. Frustaci, J. Kajstura, C. Chimenti, Igor Jakoniuk, A. Leri, A. Maseri, B. Nadal-Ginard, P. Anversa. Circulation Research, 2000
847 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine, Pathology and Forensic Medicine
View Paper: https://www.semanticscholar.org/paper/693ea8c6bb4f883bb8e95567b54ec2340e53d58b
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In Cardiology and Cardiovascular Medicine
Citations in the corpus
- Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications. (2004, background): “Up-regulation of the local renin-angiotensin system in diabetes may enhance oxidative damage, activating cardiac cell apoptosis and necrosis (114).”
- Molecular mechanisms of diabetic cardiomyopathy (2014, neutral): “Increased cell death is frequently observed in hearts of humans with type 1 and type 2 diabetes and rodent models of these disorders, and includes both apoptotic and necrotic cell death [40–44].”
- New insights on oxidative stress and diabetic complications may lead to a "causal" antioxidant therapy. (2003, background): “Increased apoptosis of myocytes, endothelial cells, and fibroblasts in heart biopsies from diabetic patients (46), in hearts from streptozotocin-induced diabetic rats (47), and in working hearts from rats during hyperglycemia (44) is selectively associated with levels of nitrotyrosine found in those”
- Oxidative stress in the placenta (2004, background): “Protein tyrosine nitration has been detected under apparently normal physiologic conditions (Greenacre and Ischiropoulos 2001) in numerous tissues including endothelial cells, fibroblasts, and vascular smooth muscle cells (Davidge et al. 1998; Frustaci et al. 2000; Kajstura et al. 2001).”
- Diabetic cardiomyopathy, causes and effects (2010, background): “ROS can also interact with other molecules such as nitric oxide (NO) to form nitrotyrosine species, which were found to be elevated in myocardial biopsies of humans with Type 2 diabetes [37].”
- Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway. (2002, background): “Recent studies showed that the incidence of apoptosis increases in the heart of patients with diabetes (20) and STZ-induced diabetic animals (21,22).”