Chemokine receptors and their role in inflammation and infectious diseases.

By Craig Murdoch, Adam Finn. Blood, 2000

895 citations recorded by the source corpus.

Subfields: Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/65cbcbcc59bfa6f4e3e19e5e9116a26e3a6a78bd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. T. Foster
2. C. Lewis
3. M. Goebeler
4. R. Gillitzer
5. Craig Murdoch
6. A. Giannoudis
7. J. Pollard
8. D. Hanahan

In Oncology

1. T. Foster
2. C. Lewis
3. M. Goebeler
4. R. Gillitzer
5. J. Pollard

Citations in the corpus

• Chemokines in cutaneous wound healing (2001, background): “It is well-known that chemotactic responses saturate with increasing concentrations of attractants specific for one receptor, which is a result of unresponsiveness (desensitization) and down-regulation of the receptor [19].”
• Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. (2004, background): “These are divided into four subclasses (CXC, CC, C and CX3C) and the specific effects of these molecules on their target cells are mediated by members of a family of seven-transmembrane, G-protein-coupled receptors.(28,29) From research carried out over the past two decades it has become increasingl”
• CCL18 from Tumor-Associated Macrophages Promotes Breast Cancer Metastasis via PITPNM3 (2011, neutral): “We next measured the intracellular calcium ([Ca 2+ ] i ) changes upon CCL18 stimulation using calcium mobilization assay, which has been commonly used to measure chemokine receptor activation (Murdoch and Finn, 2000).”
• Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. (2006, background): “Furthermore, even if chemokines, being potent inducers of leukocyte infiltration into inflamed tissue [25], should be regarded as potential interesting mediators in NAFLD, the literature is virtually devoid of data on serum levels of chemokines in this disorder.”
• Immune evasion by staphylococci (2005, background): “The peptide fragments C3a and C5a, released by complement activation, as well as formylated peptides secreted from growing bacterial cells, are recognized at high affinity by specific transmembrane G-protein-coupled receptors on the neutrophil surfac”