Emotion circuits in the brain.

By Joseph E LeDoux. Annual Review of Neuroscience, 2009

4,404 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/628992cf0818029f0624aad75e4a83f3ce3be1aa

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In Cognitive Neuroscience

Citations in the corpus

Behavioral inhibition: linking biology and behavior within a developmental framework. (2005, background): “The Effects of Emotion on Attentional Orienting One of the adaptive functions of the behavioral inhibition system is that it functions to increase vigilance and orienting to environmental cues that could be indicative of threat (LeDoux 2000).”
How brains beware: neural mechanisms of emotional attention. (2005, background): “The amygdala is known to be crucial for fear processing and fear learning, but presumably also important for a wider range of functions related to affective pertinence [39] and reflexive emotional reactions [ 38 ] .I t is well positioned to modulate perceptual processing because not only does it rec”
Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans (2005, background): “2), which are prominent among the brainstem areas to which the central nucleus of the amygdala projects (LeDoux, 2000) and which mediate fear behavior and arousal (LeDoux et al.”
Developing constructs for psychopathology research: research domain criteria. (2010, neutral): “The psychology of fear has been studied in a large number of contexts and across a number of species and is relatively well developed (see e.g., Delgado, Olsson, & Phelps, 2006; LeDoux, 2000; Quinn, Ma, Tinsley, Koch, & Fanselow, 2008).”
Who Develops Posttraumatic Stress Disorder? (2004, background): “Research has centered on the amygdala and hippocampus, key brain areas involved in the fear response and in the consolidation of memory (e.g., LeDoux, 2000), as well as on the hypothalamic-pituitary-adrenal (HPA) axis, the parts of the neuroendocrine system that control reactions to acute stress.”
The Neurobiology of Parental Behavior (2003, background): “Also relevant is the long-standing knowledge of the involvement of the amygdala in emotion, fear, and anxiety-related processes (Davis, 1992; LeDoux, 2000; Pitkänen, Savander, & LeDoux, 1997).”
How Does Mindfulness Meditation Work? Proposing Mechanisms of Action From a Conceptual and Neural Perspective (2011, positive): “…in both human and animal studies as playing a crucial role during the acquisition and expression of conditioned fear (Davis & Whalen, 2001; LeDoux, 2000; Pare, Quirk, & Ledoux, 2004; Phelps & LeDoux, 2005), including the detection of stressful and threatening stimuli and the initiation of…”
A time of change: behavioral and neural correlates of adolescent sensitivity to appetitive and aversive environmental cues. (2010, background): “a critical role in processing information of biological significance (Aggleton, 2000; Davis & Whalen, 2001; LeDoux, 2000), including emotionally evocative stimuli, potential threats, and cues depicting the emotional states of others.”
Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat (2007, background): “…suggests that BLA to mPFC projections (particularly to IL/PL) convey information on the emotional properties of sensory stimuli (Garcia et al. 1999; LeDoux 2000; Pare et al. 2004; Gabbott et al. 2006; Vertes 2006), involved in executive functions of the mPFC Non-Limbic Cortex Basal Forbrain…”
Memory Consolidation of Auditory Pavlovian Fear Conditioning Requires Protein Synthesis and Protein Kinase A in the Amygdala (2000, background): “…identifying the neuroanatomical and cellular events underlying Pavlovian fear conditioning, particularly auditory fear conditioning, which is thought to involve alterations in synaptic transmission in the lateral nucleus of the amygdala (LA) (Davis, 1997; Fanselow and LeDoux, 1999; LeDoux, 2000).”
Measures of emotion: A review (2009, neutral): “At the outset, it must be mentioned that any complex reaction such as an emotional state is likely to involve circuits rather than any brain region considered in isolation (Kagan, 2007; LeDoux, 2000; Storbeck, Robinson, & McCourt, 2006).”
Towards the neurobiology of emotional body language (2006, neutral): “The amygdala seems to be particularly involved in the assignment of signal relevance 17,75,91–93 and, as a consequence, in the modulation of brain structures that control behaviour.”
Don't fear ‘fear conditioning’: Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear (2017, positive): “Animal experimental work provides a richness of inspiration for translational studies for human behavioural (neuro)scientists and there is a wealth of information available today derived from animal experiments on the behaviour, neurobiology and pharmacology of the acquisition (Davis et al., 1993; L”
Developmental trajectories of childhood anxiety: Identifying continuity and change in anxious emotion ☆ (2008, background): “That anxiety is a higher order feeling state (Damasio, 2003) produced by the brain mechanisms responsible for basic emotion—primarily those brain mechanisms involved in physiological arousal and fear responses but also those involved with negative affect and behavioral avoidance (Baving, Laucht, & S”
The role of the amygdala in emotional processing: a quantitative meta-analysis of functional neuroimaging studies. (2008, result): “Overall, these studies have confirmed the critical role of the amygdala in emotion, in agreement with findings from research on experimental animals (LeDoux, 2000) and neurological patients (Adolphs and Spezio, 2006).”
Dendritic calcium spikes induce bi-directional synaptic plasticity in the lateral amygdala. (2007, positive): “NMDA receptor-dependent long-term potentiation (LTP) in the lateral amygdala (LA) is thought to underlie the acquisition of classical Pavlovian fear conditioning (LeDoux, 2000; Maren, 2001).”
Cortico-Basal Ganglia Reward Network: Microcircuitry (2009, neutral): “The amygdala is a region involved in expression of emotion and in learned emotional behaviors (LeDoux, 2000).”