Abnormal sensitization and temporal summation of second pain (wind‐up) in patients with fibromyalgia syndrome

By R. Staud, C. Vierck, R. L. Cannon, A. Mauderli, Donald D. Price. Pain, 2001

775 citations recorded by the source corpus.

Subfields: Pharmacology, Physiology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/622ca0b6412876ae2bd444a951031db820cfab01

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Pharmacology

1. Clifford J. Woolf
2. M. Yunus
3. R. Ji
4. Katja Wiech
5. Irene Tracey
6. Arne May

In Physiology

1. Clifford J. Woolf
2. M. Yunus
3. R. Ji
4. Arne May
5. Jürgen Sandkühler
6. G. Moalem-Taylor
7. P. Austin

In Psychiatry and Mental health

1. Clifford J. Woolf
2. M. Yunus
3. R. Neblett
4. Katja Wiech
5. Irene Tracey

Citations in the corpus

• Central sensitization: Implications for the diagnosis and treatment of pain (2010, background): “…different [87], while the secondary hyperalgesia elicited by intradermal capsaicin was shown by yet other investigators, to be restricted to mechanical stimuli, with no correlation between the magnitude of capsaicin evoked pain and the extent of punctate or tactile secondary hyperalgesia [237].”
• Pain mechanisms: labeled lines versus convergence in central processing. (2003, background): “This perspective offers new prospects for understanding mysterious pain conditions, such as fibromyalgia (deep aches and pain), that may depend on homeostatic dysfunction instead of outright tissue damage (e.g., see Staud et al. 2001).”
• Widespread pain in fibromyalgia is related to a deficit of endogenous pain inhibition (2005, background): “It has been demonstrated that FM patients are centrally sensitized (Staud et al., 2001, 2004a) and that supraspinal descending facilitatory influences appear to contribute to the development and maintenance of central sensitization (Urban and Gebhart, 1999).”
• Fibromyalgia and overlapping disorders: the unifying concept of central sensitivity syndromes. (2007, background): “Fibromyalgia patients are hypersensitive to heat (6466,68,72-77), cold (64-66,68,75,76), cutaneous electric (66,69,78), intramuscular electric (69,70), sural nerve electric (to assess nociceptive spinal reflex) (64,79), ischemic (65), and intramuscular hypertonic saline (69,70).”
• Studying sex and gender differences in pain and analgesia: a consensus report. (2007, background): “For instance, evaluation of pain sensitivity at asymptomatic body sites can reveal information about general pain-processing alterations, as has been shown for fibromyalgia [118,189], various types of headaches [182], and temporomandibular disorders (TMD) [175].”