GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway.

By Shefali Sabharanjak, Pranav Sharma, Robert G. Parton, S. Mayor. Developmental Cell, 2002

707 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/6147506e9eee1b012e8d86ad977eabd4eb805bea

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. S. Mayor
2. Robert G. Parton
3. K. Simons
4. L. Rajendran
5. Aurélien Roux
6. P. Le
7. I. Nabi
8. A. A. Richards

In Molecular Biology

1. K. Simons
2. Robert G. Parton
3. S. Mayor
4. L. Rajendran
5. Aurélien Roux
6. G. Nicolson
7. C. Dart
8. Berislav Zlokovic

In Physiology

1. S. Mayor
2. Robert G. Parton
3. K. Simons
4. P. Le
5. I. Nabi
6. A. A. Richards
7. C. Dart
8. R. Pagano

Citations in the corpus

• Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells (2006, background): “Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes.”
• Nanoscale organization of multiple GPI-anchored proteins in living cell membranes. (2004, methodology): “In sphingolipid-depleted cells, other lipids such as phos- anchor as in the case of FR-GPI and GFP-GPI (Sabharanjak et al., 2002), prevents endocytosis via the GEECphatidylcholine may substitute, albeit poorly for the functions of sphingolipids.”
• Lipid rafts and membrane dynamics (2005, background): “In addition, there is evidence for other raft-mediated routes of internalisation (Lamaze et al., 2001; Sabharanjak et al., 2002).”
• Dynamic Partitioning into Lipid Rafts Controls the Endo-Exocytic Cycle of the αL/β2 Integrin, LFA-1, during Leukocyte Chemotaxis (2005, background): “An increasing number of membrane-associated proteins has been recently reported to be endocytosed and sorted via DRM and caveolae (Fivaz et al., 2002; Sabharanjak et al., 2002; Kirkham and Parton, 2005).”
• Lipid Rafts and Caveolae as Portals for Endocytosis: New Insights and Common Mechanisms (2003, background): “This is a micropinocytic pathway specific for unclustered GPI-anchored proteins, which is not dependent on ligand binding and is also independent of both clathrin and dynamin function (107).”
• Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. (2005, background): “, 2000), two proteins shown to participate in at least some form of endocytosis (Benesch et al., 2005; Garrett et al., 2000; Innocenti et al., 2005; Sabharanjak et al., 2002).”
• Caveolae/raft-dependent endocytosis (2003, background): “In contrast, a defining feature of the pinocytotic pathway is its insensitivity to dynamin inhibition (Damke et al., 1994; Llorente et al., 1998; Contamin et al., 2000; Sabharanjak et al., 2002).”