Acetylation of Histones and Transcription-Related Factors

By D. Sterner, S. Berger. Microbiology and Molecular Biology Reviews, 2000

1,872 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/6073f3588bee07dd1d73e1bb2a5375c794d27e26

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Citations in the corpus

Antiviral Actions of Interferons (2001, background): “ferase (HAT) activity (397, 446), and also BRCA1 (306).”
HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention (2007, background): “Since then, over 60 of them have been shown to be subjected to Ne-acetylation (for reviews, see Kouzarides, 2000; Sterner and Berger, 2000; Cohen and Yao, 2004; Yang and Grégoire, 2007).”
Circadian regulator CLOCK is a histone acetyltransferase. (2006, neutral): “This would suggest that BMAL1 may critically contribute to structural conformational changes of CLOCK, a scenario reminiscent of several other HAT proteins that exhibit full activity only when functioning within a large protein complex in vivo (Sterner and Berger, 2000).”
Posttranslational Protein Modification in Archaea (2005, background): “Since then, acetylation has been reported to modulate the function of many eucaryal and a limited number of bacterial proteins (237, 416, 479).”
Histone-deacetylase inhibitors: novel drugs for the treatment of cancer (2002, background): “Mechanisms of transcriptional repression by the t(8;21)-, t(12;21)-, and inv(16)-encoded fusion proteins.”
The Mammalian SIR2α Protein Has a Role in Embryogenesis and Gametogenesis (2003, background): “In mammals, a large number of nuclear proteins in addition to histones are acetylated (44), and in the cases of some important nuclear proteins such as retinoblastoma (11) and p53 (38, 51), it is thought that acetylation plays a role in regulating the function of these transcription regulators.”
A chromatin landmark and transcription initiation at most promoters in human cells. (2007, background): “Similarly, histone acetylation has been associated with actively transcribed genes (Sterner and Berger, 2000).”
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. (2001, background): “The important discoveries include: (1) Several transcriptional coactivators such as Gcn5, p300/CBP, PCAF, TAF250, and the p160 family of nuclear receptor coactivators contain intrinsic HAT activity (Sterner and Berger 2000; Roth et al. 2001).”
Histone acetylation: a switch between repressive and permissive chromatin (2002, background): “With the identification of transcription activators and co-activators as dedicated histone acetyltransferases (HATs), it became possible to document the relationships between histone acetylation and gene activation in many cases (Sterner and Berger, 2000; Chen et al., 2001; Roth et al., 2001).”