Mechanical processes in biochemistry.

By C. Bustamante, Y. Chemla, N. R. Forde, D. Izhaky. Annual Review of Biochemistry, 2004

726 citations recorded by the source corpus.

Subfields: Atomic and Molecular Physics, and Optics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5da503652bb49718a00b68078706b23780984f6e

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In Atomic and Molecular Physics, and Optics

In Molecular Biology

Citations in the corpus

Nanonetworks: A new communication paradigm (2008, background): “teins or protein complexes that transform chemical energy into mechanical work at a nano-scale [16].”
A survey on bio-inspired networking (2010, background): “ganisms, nano-machines called molecular motors, such as dynein, myosin [97], realize intracellular communication through chemical energy transformation.”
Dynamic molecular processes mediate cellular mechanotransduction (2011, neutral): “Notably, both the strength of the force and the rate of application affect the rates of protein conformational change”
Green function of correlated genes in a minimal mechanical model of protein evolution (2018, methodology): “In view of this, we define the fitness as the maximum of F [2] over all potential locations of the channel’s output (typically 8−10 sites, Methods).”
Mechanical stretching of proteins—a theoretical survey of the Protein Data Bank (2007, background): “Table 1 is an updated version of the tables presented in [18], [31] and [32] for 4, 8 and 21 proteins, respectively.”
Biomolecules under mechanical force (2010, background): “Most insights into the unfolding through a poremechanismwere inferred from single-molecule pulling experiments [6] on polypeptide chains which unfold in free space.”
Quantum metrology and its application in biology (2014, background): “ten occurring at kilohertz timescales; the molecular motor kinesin takes steps with a characteristic time of 5 ms (200 Hz), while the motor myosin steps with a characteristic time of 660 s (1.5 kHz) [120]. As studies progress to single molecules, the frequencies can reach megahertz; for instance, li”
Theory, analysis, and interpretation of single-molecule force spectroscopy experiments (2008, background): “Other biomolecules such as higher-order nucleic acid complexes are unraveled in a controlled way by mechanical forces before being processed by polymerases, helicases, and ribosomes (1).”
Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective (2012, background): “The equation (50) implies that we can write the individual rate constants for the forward and reverse transitions as [260, 261, 262, 264]”
Protein folding studied by single-molecule FRET. (2008, background): “Experiments using atomic force microscopy and laser tweezers have provided important and previously inaccessible information on the mechanical stability and folding of proteins, and the reader is referred to a number of recent reviews on this topic [1–5].”
Revealing Early Steps of α2β1 Integrin-mediated Adhesion to Collagen Type I by Using Single-Cell Force Spectroscopy (2007, background): “Because it is known that the measured strengths of a bond strongly depends on the pulling direction (Bustamante et al., 2004), this may cause further variations in the unbinding force.”
Nonequilibrium fluctuations in small systems: From physics to biology (2007, background): “1 Single molecule force experiments In single molecule force experiments it is possible to apply force on individual molecules by grabbing their ends and pulling them apart [74, 75, 76, 77].”
Local force and geometry sensing regulate cell functions (2006, background): “Furthermore, it is well known that enzymes exert strain on their substrates on binding — thereby catalysing the reaction (reviewed in Ref”
Stochastic thermodynamics, fluctuation theorems and molecular machines (2012, background): “The fluctuating conformations of biomolecules in non-equilibrium can be described in two ways [34, 394, 395].”