Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

By M. Prince, R. Sivanandan, Andrew J. Kaczorowski, G. Wolf, Michael J. Kaplan, Piero Dalerba, Irving L. Weissman, M. Clarke, L. Ailles. Proceedings of the National Academy of Sciences of the United States of America, 2007

2,256 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/5c68191bc3a583fc9f36649735d25e3248738b65

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. J. Dick
2. Irving L. Weissman
3. Hans Clevers
4. Antonija Krešo

In Molecular Biology

1. Hans Clevers
2. Austin G Smith
3. J. Dick
4. Nick Barker
5. M. Wicha
6. R. DePinho
7. M. Clarke
8. P. Dirks

In Oncology

1. Hans Clevers
2. J. Dick
3. Antonija Krešo
4. Nick Barker
5. M. Clarke
6. M. Wicha
7. Suling Liu
8. Piero Dalerba

Citations in the corpus

• Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts (2013, background): “Subsequently, CD44, CD24, and ALDH were reported to be expressed in CSCs from a wide variety of carcinomas, including those of the pancreas, colon, lung, ovary, and prostate gland (Eramo et al., 2008; Huang et al., 2009; Kryczek et al., 2012; Li et al., 2007; Prince et al., 2007).”
• The intestinal stem cell. (2008, background): “…has been highly successful in the identification of the hematopoietic stem cell from bone marrow (Spangrude et al. 1988) and—more recently—of cancer stem cells in leukemias (Bonnet and Dick 1997) and in solid tumors (Singh et al. 2004; Dalerba et al. 2007; O’Brien et al. 2007; Prince et al. 2007).”
• Human Melanoma Initiating Cells Express Neural Crest Nerve Growth Factor Receptor CD271 (2010, positive): “Identifications of cancer stem cells (CSCs) in solid tumors3, 5-9 provided evidence that CSC appear to recapitulate the developmental program of corresponding normal tissue stem or progenitor cells, although in an incomplete and disorganized manner10.”
• Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. (2009, background): “CD44 has been used to enrich for putative cancer stem cells in other types of solid cancer, such as breast, head and neck, and pancreas and prostate (Al-Hajj et al., 2003; Patrawala et al., 2006; Li et al., 2007; Prince et al., 2007).”
• Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma (2011, background): “CD44 is a cell surface marker that has been shown to be highly expressed in putative head and neck cancer stem cells [196-200].”
• Evolution of the cancer stem cell model. (2014, background): “…in breast cancer, a plethora of papers have been published identifying CSCs in numerous cancers including brain (Singh et al., 2004), head and neck (Prince et al., 2007), pancreas (Hermann et al., 2007; Li et al., 2007), lung (Eramo et al., 2008), prostate (Collins et al., 2005; Patrawala et al.,…”