Neurotrophin signalling in health and disease.

By M. Chao, Rithwick Rajagopal, F. Lee. Clinical science, 2006

625 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/5b67d613b262ef700be8dce1d6d5f0d1ba003b37

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In Cellular and Molecular Neuroscience

In Developmental Neuroscience

Citations in the corpus

Brain-Derived Neurotrophic Factor and Neuropsychiatric Disorders (2012, methodology): “Furthermore, the use of recombinant BDNF molecules has not been successful in clinical trials because of side effects (Chao et al., 2006), inability to cross the blood-brain barrier with systemic treatment, and complications associated with surgical infusion of proteins directly into the brain…”
GDNF, NGF and BDNF as therapeutic options for neurodegeneration. (2013, background): “…neurotrophins, and interacts with several other proteins including NRAGE, NRH2 and NRIF to promote neurite outgrowth, proliferation and cell death (Chao et al., 2006). p75NTR in the adult forebrain, is mainly located on neurons in the ChBF and its projections, with some present in certain parts…”
PathNet: a tool for pathway analysis using topological information (2012, positive): “The luteinizing hormone is known to be involved in the formation of beta amyloid (A β ), which is a pathological hallmark of AD [46,47], and the neurotrophin signaling pathway regulates the signaling of neurons [48].”
Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. (2007, background): “Consistent with an increase in NAc BDNF protein, we also observed a robust activation of signaling molecules downstream of TrkB (Chao et al., 2006).”
Mouse and rat BDNF gene structure and expression revisited (2006, background): “…acid Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family consisting of small secreted proteins that play important roles in the development of the nervous system in vertebrates (for recent reviews see Bibel and Barde, 2000; Binder and Scharfman, 2004; Chao et al., 2006).”
A TALE nuclease architecture for efficient genome editing (2011, background): “Our target for these studies was the human NTF3 gene, which encodes a secreted nerve growth factor that has therapeutic potential for neurodegenerative disease”
Axon-glial signaling and the glial support of axon function. (2008, background): “They also play a role in dendritic pruning and neurotransmitter release and have been implicated in neurodegenerative diseases (reviewed in Chao et al. 2006).”