Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions.

By V. Krishnan, Ming-Hu Han, Danielle L. Graham, O. Berton, W. Renthal, S. Russo, Q. LaPlant, Ami Graham, Michael Lutter, D. Lagace and 14 more. Cell, 2007

2,195 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cellular and Molecular Neuroscience, Social Psychology

View Paper: https://www.semanticscholar.org/paper/01e6930481a95dd7197434c7c30051d6495dff4f

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Citations in the corpus

Neurobiological and Systemic Effects of Chronic Stress (2017, background): “These alterations are implicated in increased anxiety and in posttraumatic stress disorder (PTSD)-like behaviors(18,21) as well as social avoidance as in social defeat.(20,22) Within the prefrontal cortex (PFC), chronic stress causes medial PFC (mPFC) neurons to show debranching and shrinkage of den”
Brain-Derived Neurotrophic Factor and Neuropsychiatric Disorders (2012, background): “Studies have revealed that BDNF protein is increased in the nucleus accumbens (NAc) tissue from human patients with MDD (Krishnan et al., 2007).”
Linking Molecules to Mood: New Insight Into the Biology of Depression (2010, neutral): “This is a genuinely difficult requirement, but has been gaining increasing popularity with the more widespread access to postmortem samples (12-15).”
Depression: An Evolutionarily Conserved Mechanism to Terminate Separation Distress? A Review of Aminergic, Peptidergic, and Neural Network Perspectives (2009, background): “…Kroes et al., 2006; Panksepp et al., 2004, 2007), with the most comprehensive analysis having appeared recently characterizing the massive gene-expression changes in the brain that result differentially in varying degrees of “resilience” to this classic stress paradigm (Krishnan et al., 2007).”
Social functioning in major depressive disorder. (2016, positive): “Individual differences in response to this social stress lead to a group of mice that continue to display normal social approach and interaction, termed „resilient‟ and a group that demonstrate social avoidance, termed „susceptible‟ (Krishnan et al., 2007).”
The resilience framework as a strategy to combat stress-related disorders (2017, positive): “…animal models have been able to describe adaptive changes in the neural systems affected by stressor exposure specifically in animals that recovered well from stressor-induced behavioural dysfunctions; these studies also demonstrated the causal nature of these neural adaptations in recovery 24–27 .”