Mechanisms of angiogenesis and arteriogenesis

By Peter Carmeliet. Nature Medicine, 2000

4,372 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/5a1d3e5179749fc4d0de793408de9d8beda8bd1d

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Citations in the corpus

Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells (2003, background): “In analogy to the embryonic development of blood vessels from primitive endothelial progenitors (angioblasts), this process is referred to as 'vasculogenesis”
Vascularization and Angiogenesis in Tissue Engineering: Beyond Creating Static Networks. (2016, background): “Mural cells proliferate, and acquire specialized characteristics, including contractile components [14].”
Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. (2005, background): “To induce angiogenesis and/or arteriogenesis, tight orchestration of monocytes/macrophages, ECs, and SMCs/pericytes is critical (22, 43).”
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. (2000, background): “After the initial formation of the vascular plexus, vessels mature by the stabilization of the endothelial vascular network through a recruitment and differentiation process that ultimately results in the investment of vessel walls with mural cells (26).”
Scatter-factor and semaphorin receptors: cell signalling for invasive growth (2002, background): “Intratumoral angiogenesis produces a vascular network that is in close contact with the neoplastic cells, which can penetrate the capillary walls and enter the circulatio”
Endoglin promotes endothelial cell proliferation and TGF‐β/ALK1 signal transduction (2004, background): “Angiogenesis is a carefully regulated process, which can be viewed as two separate, but balanced phases, activation and resolution, that lead to blood vessel formation from a pre-existing vascular network (Risau, 1997; Carmeliet, 2000).”
VEGF and the quest for tumour angiogenesis factors (2002, background): “Although recent evidence indicates that new vessel growth and maturation are highly complex and coordinated processes, requiring the sequential activation of a series of receptors by numerous ligand”
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. (2003, background): “Vascularization is initiated by various factors ranging from mechanical stress and hypoxia to the presence of soluble inflammatory mediators (16) and involves the sprouting of small capillaries (angiogenesis) and the growth of preexisting vessels (arteriogenesis).”
To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. (2010, background): “Hypoxia increases cellular hypoxia inducible factor (HIF) transcription, leading to upregulation of pro-angiogenic proteins such as vascular endothelial growth factor (VEGF), platelet derived growth factor (PDGF) or tumor necrosis factor-α (TNF-α) [12].”
Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration (2010, background): “Next, vascular loops are formed and capillary tubes develop with the formation of tight junctions and deposition of new basement membrane [59].”
Angiogenesis in cancer and other diseases (2000, background): “We now know there are various molecular players involved in these different mechanisms of vascular growt”
Pharmacological Treatment of Coronary Artery Disease With Recombinant Fibroblast Growth Factor-2: Double-Blind, Randomized, Controlled Clinical Trial (2002, neutral): “Death, n (%) 1 (1) 1 (1) 3 (3) 1 (1) Carcinoma, n (%) 1 (1) 0 1 ( 1 ) 1 (1)”
Molecular mechanisms of blood vessel growth. (2001, neutral): “The plasma [96].”