Ageing as a risk factor for disease.

By T. Niccoli, Linda Partridge. Current Biology, 2012

1,609 citations recorded by the source corpus.

Subfields: Aging, Physiology

View Paper: https://www.semanticscholar.org/paper/5940a4db81f751af30aabc5d7826c32fb27d5647

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Aging

1. J. Kirkland
2. T. Tchkonia
3. T. Wyss‐Coray
4. J. Rutledge
5. Jesús Gil
6. H. Oh
7. Domhnall McHugh

In Physiology

1. J. Kirkland
2. T. Tchkonia
3. Jesús Gil
4. T. Wyss‐Coray
5. J. Rutledge
6. H. Oh
7. Domhnall McHugh
8. J. Campisi

Citations in the corpus

• Age and Cancer Risk (2014, neutral): “Whether the relationship between age and cancer risk is due primarily to the timedependent accumulation of genetic and epigenetic mutations or to an increased susceptibility of older adults to oncogenic mutations is not fully understood.(30,31) The multifactorial process of transformation from norma”
• Cellular senescence and senolytics: the path to the clinic (2022, background): “The first senolytic agents intentionally selected for further investigation were ones that: (1) target several SCAPs, rather than adhering to the traditional drug development approach of one drug/one molecular target/one disease, (2) can be administered orally, and (3) are natural products with know”
• Senescence and aging: Causes, consequences, and therapeutic avenues (2018, background): “Consequently, age is a risk factor for many diseases (Niccoli and Partridge, 2012), such as cardiovascular disease (North and Sinclair, 2012), dementia (Querfurth and LaFerla, 2010), osteoporosis (Raisz, 1988), osteoarthritis (Raisz, 1988), cancer (de Magalhães, 2013), type 2 diabetes (Gunasekaran a”
• Human Ageing Genomic Resources: new and updated databases (2017, background): “As lifespan increases so too does the prevalence of these diseases (38).”
• Measuring biological age using omics data (2022, background): “Ageing contributes to many diseases that affect all organ systems and is the greatest risk factor for heart disease, neurodegeneration and cancer 2 .”
• Liquid-Liquid Phase Separation in Disease. (2019, background): “In most diseases, including neurodegenerative diseases, aging is the most common risk factor (115).”