The physiology of the lymphatic system.

By M. Swartz. Advanced Drug Delivery Reviews, 2001

731 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/58adaa54233098ef37174c773617fc6fde9e673b

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In Molecular Biology

1. N. Bertrand
2. N. Kamaly
3. M. Bachmann
4. Xiaoyang Xu
5. G. Jennings
6. Jun Wu
7. M. Üner
8. G. Yener

In Oncology

1. M. Bachmann
2. G. Jennings
3. H. Wiig
4. G. Randolph
5. M. Üner
6. G. Yener
7. V. Angeli
8. O. Farokhzad

Citations in the corpus

• Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives (2007, background): “…in particle size related to the PEG concentration in the formulations and a decrease in murine uptake compared with non-stealth SLN. Optimum particle size for lymphatic uptake was reported to be between 10 and 100 nm and to be selective and slower as the particle size increases (Swartz 2001).”
• Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. (2014, background): “While molecules smaller than 4 nm can diffuse back to the blood circulation and be reabsorbed [48-50], the diffusion of macromolecules or NPs is hindered by their larger hydrodynamic radii.”
• Dendritic-cell trafficking to lymph nodes through lymphatic vessels (2005, background): “Lymph flow is unidirectional from the periphery to the heart: the lymph absorbs interstitial fluid from tissues and, eventually, returns it to the blood circulation at the thoracic duct, passing through the lymph nodes en route”
• Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns (2010, background): “These cells function as flap valves that ensure unidirectional transport of solutes and small particles along the lymphatic vessel”
• Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer. (2012, background): “Lymph nodes are organized in clusters throughout the lymphatic system and are compartmentalized with narrow fluid crevices where the vascular compartment opposes each lymph compartment for fluid exchange and cell transport (375, 448).”
• Vaccine adjuvants: mechanisms and platforms (2023, background): “Besides, in this approach, the delivery system is optimally charged to carry a net negative charge, rather than a net positive charge, since the interstitial matrix of the afferent lymphatic vessels is composed mainly of collagen fibers and negatively charged glycosaminoglycans.(107) In addition, th”