Chronic Stress Induces Contrasting Patterns of Dendritic Remodeling in Hippocampal and Amygdaloid Neurons

By A. Vyas, R. Mitra, B. S. Shankaranarayana Rao, Sumantra Chattarji. Journal of Neuroscience, 2002

1,693 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Biological Psychiatry, Social Psychology

View Paper: https://www.semanticscholar.org/paper/587bd6bf61952d2c4d4fa8f4155737d79006655e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. Bruce S. McEwen
2. Margaret A Sheridan
3. Nim Tottenham
4. J. Wingfield
5. John H. Morrison
6. S. Salim
7. R. Duman
8. Peter J. Gianaros

In Biological Psychiatry

1. Bruce S. McEwen
2. Margaret A Sheridan
3. J. Wingfield
4. Nim Tottenham
5. R. Duman
6. G. Sanacora
7. B. Casey
8. Peter J. Gianaros

In Social Psychology

1. Bruce S. McEwen
2. Margaret A Sheridan
3. Nim Tottenham
4. B. Casey
5. R. Duman
6. G. Sanacora
7. M. Popoli
8. Marian Joëls

Citations in the corpus

• Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms (2008, background): “In rats, stress that leads to atrophic changes in hippocampal pyramidal cells produces enhanced dendritic length and branching in amygdala principal cells and in the bed nucleus of the stria terminalis, an important amygdala projection target (Vyas et al, 2002, 2003).”
• Stress signalling pathways that impair prefrontal cortex structure and function (2009, neutral): “By contrast to the PFC and hippocampus, dendrites in the amygdala expand in response to chronic stress exposur”
• Brain On Stress: Vulnerability and Plasticity of the Prefrontal Cortex Over the Life Course (2013, positive): “…caused dendritic shortening in medial prefrontal cortex (Cerqueira et al., 2007; Cook and Wellman, 2004; Liston et al., 2006; Radley et al., 2004) but produced dendritic growth in neurons in basolateral amygdala (Vyas et al., 2002), as well as in orbitofrontal cortex (Liston et al., 2006).”
• Structural plasticity and memory (2004, background): “Stress also induces structural changes in the hippocampus and amygdal”
• Stress and Memory: Behavioral Effects and Neurobiological Mechanisms (2007, neutral): “[138, 139]; Mitra et al.”
• Towards a glutamate hypothesis of depression (2011, background): “The same stress paradigms, that induced reduction of dendrite arborization and spine density in hippocampus and medial prefrontal cortex, increased dendritic length and spine density in amygdala, at the same time enhancing behavioral measures of anxiety (Vyas et al., 2002, 2004).”
• Stress and the brain: from adaptation to disease (2005, background): “By contrast, repeated immobilization stress causes hypertrophy in the basolateral amygdal”
• The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission (2011, background): “The brain is also a target of stress, with animal models showing stress-induced remodelling of brain architecture, such as dendritic atrophy and loss of dendritic spines in neuronal population”
• Protective and damaging effects of stress mediators: central role of the brain (2006, background): “Behavioral correlates of remodeling in the prefrontal cortex include impairment in attention set shifting, possibly reflecting structural remodeling in the medial prefrontal cortex.(95)”
• Oxidative Stress and the Central Nervous System (2017, positive): “And, oxidative stress–initiated neuroendocrine alterations within the amygdala, including amygdalar hyperactivity and dendritic shrinking (Wellman, 2001; Vyas et al., 2002; Kreibich and Blendy 2004; Brown et al., 2005; Radley et al., 2006; Wood et al., 2010), can further potentiate synaptic disturba”
• Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators. (2008, background): “…cortex (Sousa et al., 2000; Wellman, 2001; Vyas et al., 2002; Kreibich and Blendy, 2004; Cook andWellman, 2004; Radley et al., 2004, 2006; Brown et al., 2005) but produces dendritic growth in neurons in amygdala (Vyas et al., 2002), as well as in orbitofrontal cortex (Liston et al., 2006).”
• A Review of Adversity, The Amygdala and the Hippocampus: A Consideration of Developmental Timing (2009, positive): “This type of fi nding seems to contradict animal studies, which have identifi ed larger amygdala cell size in addition to exaggerated amygdala activity (Vyas et al., 2002, 2004).”
• Behavior Problems After Early Life Stress: Contributions of the Hippocampus and Amygdala (2014, background): “Compelling data exist that ELS is associated with volumetric increases in the amygdala (50,51,60,61) and increased amygdala activity (83–85).”
• Neural Regulation of Endocrine and Autonomic Stress Responses (2009, background): “Conversely, increased dendritic branching is observed in the BL”