Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators.

By Bruce S. McEwen. European Journal of Pharmacology, 2008

1,890 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Biological Psychiatry, Physiology

View Paper: https://www.semanticscholar.org/paper/4539d1634a572be94a61dd8b352135577b48fa33

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Citations in the corpus

Hematological differences between stingrays at tourist and non-visited sites suggest physiological costs of wildlife tourism. (2009, background): “…variation in general stingray physiology is influenced by multiple mediators and systems in a complex and non-linear fashion; and denotes there are enormous individual differences in the response to stressors, based upon the experience of the individual in early and in adult life (McEwen, 2008).”
The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis (2018, background): “Exposition to multiple repeated stressors counteracts the parasympathetic tone recovery, favoring an allostatic load (McEwen, 2008) thus blunting the anti-inflammatory regulatory action of the VN.”
Allostatic load biomarkers of chronic stress and impact on health and cognition. (2010, background): “3), delineating time-courses of dysregulation is difficult (McEwen, 2008).”
Mindfulness training and reductions in teacher stress and burnout: Results from two randomized, waitlist-control field trials. (2013, background): “On the one hand, they take a toll on physical and mental health in terms of anxiety and depression, high blood pressure, or even cardiovascular disease (Dimsdale, 2008; Gunnar & Quevedo, 2007; Maslach et al., 2001; McEwen, 2008).”
Self-awareness, self-regulation, and self-transcendence (S-ART): a framework for understanding the neurobiological mechanisms of mindfulness (2012, background): “Mindf ulness training is proposed to reduce the chance f or pathophysiological processes or unf avorable psychopathological outcomes by preventing perseverative and chronic responses in the presence or imagined presence of a stress-related physiological challenge and through ef f ective habituation ”
Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. (2012, background): “The hypothalamic–pituitary–adrenal (HPA) axis is a key endocrine adaptor against stressors and plays an important role in the pathophysiology of stress-related psychiatric diseases such as depression and anxiety disorders (de Kloet et al., 2005; McEwen, 2008; Nemeroff and Vale, 2005).”
Association of Hearing Impairment with Brain Volume Changes in Older Adults (2014, background): “…broader influence of hearing impairment on social isolation and stress (Cole, Hawkley et al., 2007, 2010) couldmediate the observed association of hearing impairment with accelerated rates of whole brain volume (McEwen, 2008; Radley and Morrison, 2005; Sapolsky, 1999) is plausible but speculative.”