Stress and the brain: from adaptation to disease

By E. D. de Kloet, Marian Joëls, F. Holsboer. Nature Reviews Neuroscience, 2005

4,641 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Endocrinology, Diabetes and Metabolism, Social Psychology

View Paper: https://www.semanticscholar.org/paper/44aaa42a4f84c18d8bf5656020dddac23f951b34

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. Terrie E. Moffitt
2. Avshalom Caspi
3. A. Danese
4. Jaak Panksepp
5. R. Hen
6. O. Almeida
7. Nuno J. Sousa
8. João J. Cerqueira

In Endocrinology, Diabetes and Metabolism

1. R. Hen
2. Jaak Panksepp
3. A. Danese
4. D. Watt
5. M. Popoli
6. G. Sanacora

In Social Psychology

1. D. Watt
2. Jaak Panksepp
3. R. Hen
4. O. Almeida
5. Nuno J. Sousa
6. João J. Cerqueira
7. T. Jay
8. A. Danese

Citations in the corpus

• Work stress precipitates depression and anxiety in young, working women and men (2007, background): “As suggested by animal and human studies, biological mechanisms could involve the dysregulation of stress hormones (i.e. glucocorticoids) (de Kloet et al. 2005).”
• Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. (2012, background): “The hypothalamic–pituitary–adrenal (HPA) axis is a key endocrine adaptor against stressors and plays an important role in the pathophysiology of stress-related psychiatric diseases such as depression and anxiety disorders (de Kloet et al., 2005; McEwen, 2008; Nemeroff and Vale, 2005).”
• The Prefrontal Cortex as a Key Target of the Maladaptive Response to Stress (2007, background): “Normally, after exposure to a stressor, adrenoglucocorticoids act in the brain to restore physiological and behavioral homeostasis (de Kloet et al., 2005); however, when the intensity or duration of stressors exceeds a certain individualspecific threshold, activation of the stress response can be…”
• Depression: An Evolutionarily Conserved Mechanism to Terminate Separation Distress? A Review of Aminergic, Peptidergic, and Neural Network Perspectives (2009, background): “In one of the most detailed reviews of these issues to date in the neuroscience literature, de Kloet, Joëls, and Holsboer (2005) elegantly summarize the basic data points for this view: • The hyperdrive of hypothalamic corticotropin-releasing hormone (CRF)/vasopressin neurons and…”
• BEHAVIORAL EFFECTS OF FLUOXETINE IN AN ANIMAL MODEL OF ANXIETY/DEPRESSION ARE MEDIATED BY BOTH NEUROGENESIS-DEPENDENT AND INDEPENDENT MECHANISMS (2009, methodology): “482 Neuron 62, 479–493, May 28, 2009 ª2009 Elsevier Inc. antidepressants was observed in corticosterone-treated (from 12.2 ± 2.3 s in corticosterone group to 31.7 ± 5.1 s and 20.3 ± 3.3 s in corticosterone/fluoxetine and corticosterone/imipramine group, respectively) and non-corticosterone-treated a”
• Stress-Induced p38 Mitogen-Activated Protein Kinase Activation Mediates κ-Opioid-Dependent Dysphoria (2007, background): “Exposure to behavioral stressors activates several neuropeptide systems, including the endogenous opioid system in the brain and spinal cord and the CRF/ACTH systems in the brain and hypothalamic pituitary axis (Herman et al., 2004; de Kloet et al., 2005).”