The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes.

By Adam Mayerson, R. Hundal, S. Dufour, V. Lebon, D. Befroy, G. Cline, S. Enocksson, Silvio E. Inzucchi, Gerald I. Shulman, K. Petersen. Diabetes, 2002

648 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/552830312d9a84bbc6ea63cfd8c3534bf141295e

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In Endocrinology, Diabetes and Metabolism

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Citations in the corpus

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. (2005, positive): “Gas chromatography/mass spectrometry analyses of the enrichment of [6,6-2 H 2 ]glucose in plasma were measured with a Hewlett-Packard Mass Selective Detector (model 5971A) as previously described (32).”
International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors (2006, background): “Among the synthetic compounds that selectively activate PPAR (cid:4) , the thiazolidinediones are insulin sensitizers used to treat the hyperglycemia of type 2 diabetes (Mayerson et al., 2002; Bajaj et al., 2003; Bays et al., 2004).”
Diabetic dyslipidaemia: from basic research to clinical practice* (2003, background): “The complement to these studies is the observation that PPAR-γ agonist in humans reduced fat in the liver [177].”
Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review (2014, background): “Rosiglitazone has proven its effectiveness in reducing insulin resistance [86–90].”
Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction? (2003, background): “These insulin sensitizers produced an 25 and 20% improvement in insulinstimulated glucose metabolism, respectively (45,46).”
Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009 (2010, background): “Magnetic resonance spectroscopic studies have demonstrated that intramyocellular and intrahepatic fat accumulation are closely associated with organ-specific insulin resistance [138–141].”