Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change.

By Jens C. Pruessner, Clemens Kirschbaum, Gunther Meinlschmid, Dirk H. Hellhammer. Psychoneuroendocrinology, 2003

3,602 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems, Food Science

View Paper: https://www.semanticscholar.org/paper/54a04a6dcd96187e8afb0ceed12b6a6b1b0a3f8d

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In Endocrine and Autonomic Systems

In Food Science

Jens C. Pruessner

Citations in the corpus

Effect of Compassion Meditation on Neuroendocrine, Innate Immune and Behavioral Responses to Psychosocial Stress (2008, background): “…increased levels of plasma IL-6 (and/or its downstream product c-reactive protein) predict the development of a number of disease states, including vascular disease, diabetes and dementia (Ridker, 2000; Pradhan et al., 2001; Kiecolt-Glaser et al., 2003; Perry et al., 2007; Steptoe et al., 2007).”
HPA axis activation by a socially evaluated cold-pressor test. (2008, methodology): “Thereafter, we computed the area under the curve with respect to increase (AUCinc; Pruessner et al., 2003) and subjected the AUCinc values to a one-way ANOVA.”
The Awakening Cortisol Response: Methodological Issues and Significance (2004, methodology): “Overall or total cortisol secretory activity can be quantified when three or more measures are available by calculation of the area under the curve (AUC) relative to zero† (or ground: AUCG) (see Pruessner et al., 2003a, for discussion of this calculation).”
Evidence for a differential role of HPA-axis function, inflammation and metabolic syndrome in melancholic versus atypical depression (2013, methodology): “37 To calculate AUCi and AUCg, samples of at least three time points had to be available.”
Dopamine Release in Response to a Psychological Stress in Humans and Its Relationship to Early Life Maternal Care: A Positron Emission Tomography Study Using [11C]Raclopride (2004, methodology): “The area under the curve (cortisol in nanomoles per liter by time in minutes) was calculated for each subject and each scanning session using a recently described method (Pruessner et al., 2003).”
Promoting Stress Management and Wellbeing in Educators: Feasibility and Efficacy of a School-Based Yoga and Mindfulness Intervention (2016, methodology): “Cortisol area under the curve (AUC) with respect to ground was computed with a formula that accounts for variability in time intervals between measurements (Pruessner et al. 2003).”
The Effect of a Real Dog, Toy Dog and Friendly Person on Insecurely Attached Children During a Stressful Task: An Exploratory Study (2011, methodology): “Further analyses of the cortisol data included the calculation of the area under the curve with respect to increase (AUCi) for the entire sampling time, as an indicator of the increase and decrease of cortisol levels over the entire experimental period, taking into account the differences in the ini”
Human salivary alpha-amylase reactivity in a psychosocial stress paradigm. (2005, methodology): “For alpha-amylase and cortisol, area under the total response curve (AUC), expressed as area under all samples, was calculated using the trapezoid formula (Pruessner et al., 2003).”
Assessment of the cortisol awakening response: Expert consensus guidelines. (2016, positive): “In addition, quantification strategies are in use, which combine information of S1 and the CAR, thus providing an index of overall cortisol secretion over the post-awakening period (e.g., the AUCG, Pruessner et al., 2003).”